3-Methoxybenzamide

Name: 3-Methoxybenzamide
Brand: TargetMol
SKU: T7439
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 98.52%

货号 T7439Cas号 5813-86-5

别名 3-甲氧基苯甲酰胺, 3-MBA

3-Methoxybenzamide (3-MBA) 是一种多聚 ADP-核糖合成酶的竞争性抑制剂，可抑制枯草芽孢杆菌的细胞分裂，诱导细胞凋亡。它可促进蓝薯植株的生长、微瘤化和转化效率。

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3-Methoxybenzamide

一键复制产品信息

很棒

纯度: 98.52%

货号 T7439 别名 3-甲氧基苯甲酰胺, 3-MBACas号 5813-86-5

规格	价格	库存
5 mg	¥ 108	现货
10 mg	¥ 139	现货
25 mg	¥ 228	现货
50 mg	¥ 367	现货
100 mg	¥ 548	现货
500 mg	¥ 1,380	现货
1 mL x 10 mM (in DMSO)	¥ 153	现货

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产品介绍

3-Methoxybenzamide AI Summary

3-Methoxybenzamide exhibits multifaceted bioactivity, including the inhibition of poly(ADP-ribose)-polymerase (PARP) with IC50 values of 17000 nM and 30000 nM reported from different sources. Additionally, it shows significant antibacterial activity against various bacterial strains. In Staphylococcus aureus ATCC 29213, it has Minimum Inhibitory Concentration (MIC) values of 2048 µg/mL under standard conditions and 4096 µg/mL in the presence of 2% bovine serum albumin. Against Bacillus subtilis, especially FtsZ mutants, the compound demonstrates higher MIC values compared to wild-type strains. It effectively inhibits FtsZ-mediated cell division in Bacillus subtilis 168 at 500 µg/mL. For Staphylococcus epidermidis ATCC 12228, the MIC value is 4096 µg/mL. Furthermore, 3-Methoxybenzamide has demonstrated bioactivity as an inhibitor in TGF-β and USP1/UAF1 assays with a potency of 31622.8 nM. The broad-spectrum antibacterial activity encompasses penicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus, penicillin-susceptible Streptococcus pyogenes, and Streptococcus pneumoniae, with MIC values ranging from >128 µg/mL to 4096 µg/mL. It also inhibits cell division in Bacillus subtilis at 512 µg/mL, as evident from phase-contrast light microscopy analyses..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
别名	3-甲氧基苯甲酰胺, 3-MBA

化学信息

分子量	151.16
分子式	C₈H₉NO₂
CAS No.	5813-86-5
Smiles	COC1=CC=CC(=C1)C(N)=O
密度	1.143g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 55 mg/mL (363.85 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.6155 mL	33.0775 mL	66.1551 mL	330.7753 mL
5 mM	1.3231 mL	6.6155 mL	13.2310 mL	66.1551 mL
10 mM	0.6616 mL	3.3078 mL	6.6155 mL	33.0775 mL
20 mM	0.3308 mL	1.6539 mL	3.3078 mL	16.5388 mL
50 mM	0.1323 mL	0.6616 mL	1.3231 mL	6.6155 mL
100 mM	0.0662 mL	0.3308 mL	0.6616 mL	3.3078 mL