规格

价格

库存

数量

1 mg

¥ 343

现货

5 mg

¥ 818

现货

10 mg

¥ 1,290

现货

25 mg

¥ 1,980

现货

50 mg

¥ 3,360

现货

100 mg

¥ 4,780

现货

200 mg

¥ 6,660

现货

1 mL x 10 mM (in DMSO)

¥ 883

现货

生物活性

产品描述	Gunagratinib (ICP-192) is an orally active and highly effective pan-FGFR (fibroblast growth factor receptor) inhibitor, used in studies of FGFR-related diseases.
体外活性	Gunagratinib 是一种新型泛成纤维细胞生长因子受体（FGFR）抑制剂，可通过共价结合有效且选择性地不可逆地抑制 FGFR 活性，具有抗肿瘤活性。[1]
别名	古那替尼, ICP-192, ICP192

化学信息

分子量	423.47
分子式	C₂₂H₂₅N₅O₄
CAS No.	2211082-53-8
Smiles	N(C)C=1N(N=C(C#CC2=CC(OC)=CC(OC)=C2)C1C(N)=O)[C@@H]3CN(C(C=C)=O)CC3
密度	1.27 g/cm3 (Predicted)

储存&溶解度

存储

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (188.92 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3614 mL	11.8072 mL	23.6144 mL	118.0721 mL
5 mM	0.4723 mL	2.3614 mL	4.7229 mL	23.6144 mL
10 mM	0.2361 mL	1.1807 mL	2.3614 mL	11.8072 mL
20 mM	0.1181 mL	0.5904 mL	1.1807 mL	5.9036 mL
50 mM	0.0472 mL	0.2361 mL	0.4723 mL	2.3614 mL
100 mM	0.0236 mL	0.1181 mL	0.2361 mL	1.1807 mL