规格

价格

库存

数量

2 mg

¥ 3,190

5日内发货

25 mg

¥ 14,300

8-10周

50 mg

¥ 18,700

8-10周

100 mg

¥ 25,500

8-10周

1 mL x 10 mM (in DMSO)

¥ 4,120

5日内发货

生物活性

产品描述	RIPK-IN-4 is a highly effective and selective small-molecule inhibitor of receptor-interacting protein kinase 2 (RIPK2) that demonstrates potent biochemical activity with an IC50 value of 3 nM, and it is further distinguished by excellent oral bioavailability, making it a valuable research tool for investigating RIPK2-mediated signaling pathways, innate immune responses, and inflammatory disease mechanisms in both in vitro and in vivo experimental systems.
靶点活性	RIPK2:3 nM
体外活性	方法：采用小鼠、大鼠和人肝微粒体进行肝微粒体稳定性实验。结果：RIPK-IN-4 在小鼠、大鼠和人肝微粒体中的提取比分别为 0.59、0.45 和 0.39[1]。
别名	RIPK 抑制剂-4

化学信息

分子量	392.45
分子式	C₁₈H₂₁FN₄O₃S
CAS No.	2141969-56-2
Smiles	O=S(=O)(C1=CN2C(=NC=C2C=3C=C(F)N=C(N)C3)C=C1OCC)C(C)(C)C
密度	1.37 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 24 mg/mL (61.15 mM), Sonication is recommended.

溶液配制表

DMSO