OTS186935 trihydrochloride, revealed significant inhibition of tumor growth in mouse xenograft models using MDA-MB-231 breast cancer cells and A549 lung cancer cells without any detectable toxicity.??SUV39H2 inhibitors sensitize cancer cells to DOX by reduction of γ-H2AX levels in cancer cells

OTS186935 trihydrochloride?exhibits growth suppressive effects in human cancer cell line derived xenograft models[1].