4-(Aminomethyl)benzoic acid

Name: 4-(Aminomethyl)benzoic acid
Brand: TargetMol
SKU: T1252
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.64%

货号 T1252Cas号 56-91-7

别名 止血芳酸, 氨甲苯酸, α-Amino-p-toluic acid, PAMBA, Aminomethylbenzoic acid

4-(Aminomethyl)benzoic acid (PAMBA) 是一种抗溶纤维蛋白药，是一种非天然氨基酸衍生物。

4-(Aminomethyl)benzoic acid

一键复制产品信息

很棒

纯度: 99.64%

货号 T1252 别名 止血芳酸, 氨甲苯酸, α-Amino-p-toluic acid, PAMBA, Aminomethylbenzoic acidCas号 56-91-7

4-(Aminomethyl)benzoic acid (PAMBA) 是一种抗溶纤维蛋白药，是一种非天然氨基酸衍生物。

规格	价格	库存	数量
500 mg	¥ 99	现货

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产品介绍

4-(Aminomethyl)benzoic acid AI Summary

4-(Aminomethyl)benzoic acid exhibits a range of bioactivities, beginning with its antibacterial properties against Helicobacter pylori ATCC 43504, Staphylococcus aureus 209P JC, and Escherichia coli K-12, with a minimum inhibitory concentration (MIC) greater than 64.0 µg/mL. In bioactivity assays, 4-(Aminomethyl)benzoic acid has a partition coefficient (logD2.0) value of 1.03, suggesting moderate lipophilicity and a potential for effective distribution within biological systems. It acts as an inhibitor of trypsin with a Ki value of 500034534.98 nM. Furthermore, 4-(Aminomethyl)benzoic acid functions as a substrate for semicarbazide-sensitive amine oxidase (SSAO) in both human and mouse models, showing no hydrogen peroxide production at 1 mM in human SSAO and 4.06% hydrogen peroxide production at 100 µM in mouse SSAO relative to benzylamine oxidation. In addition to these functions, 4-(Aminomethyl)benzoic acid demonstrates significant growth inhibitory activity across various human tumor cell lines, including breast, renal, lung, prostate, leukemia, melanoma, ovarian, colon, and central nervous system cell lines, with GI50 values of 100000.0 nM, indicating its potential utility as an anti-cancer agent..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	4-(Aminomethyl)benzoic acid (PAMBA), an antifibrinolytic, is an unnatural amino acid derivative.
别名	止血芳酸, 氨甲苯酸, α-Amino-p-toluic acid, PAMBA, Aminomethylbenzoic acid

化学信息

分子量	151.16
分子式	C₈H₉NO₂
CAS No.	56-91-7
Smiles	NCC1=CC=C(C=C1)C(O)=O
密度	1.2023 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 9.09 mg/mL (60.13 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	6.6155 mL	33.0775 mL	66.1551 mL	330.7753 mL
5 mM	1.3231 mL	6.6155 mL	13.2310 mL	66.1551 mL
10 mM	0.6616 mL	3.3078 mL	6.6155 mL	33.0775 mL
20 mM	0.3308 mL	1.6539 mL	3.3078 mL	16.5388 mL
50 mM	0.1323 mL	0.6616 mL	1.3231 mL	6.6155 mL