MS7 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme in the NAD+ biosynthesis pathway that converts nicotinamide to nicotinamide mononucleotide, which is subsequently transformed into NAD+. NAMPT is overexpressed in various cancer cells to sustain the NAD+ supply required for rapid proliferation. The derivative of MS7, PROTAC A7, serves as an effective NAMPT degrader. MS7 is utilized in cancer research.