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Anti-Neuroserpin Antibody (4G149)
还可以产品编号 TMAY-01648
别名 Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402
Anti-Neuroserpin Antibody (4G149) 是一种 Mouse 抗体，靶向 Neuroserpin。Anti-Neuroserpin Antibody (4G149) 可用于 ELISA,IHC-P。
Anti-Neuroserpin Antibody (4G149)
Anti-Neuroserpin Antibody (4G149)
还可以产品编号 TMAY-01648 别名 Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402
Anti-Neuroserpin Antibody (4G149) 是一种 Mouse 抗体，靶向 Neuroserpin。Anti-Neuroserpin Antibody (4G149) 可用于 ELISA,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Neuroserpin Antibody (4G149) is a Mouse antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (4G149) can be used in ELISA,IHC-P. |
| 别名 | Spi17, serpin peptidase inhibitor, clade I (neuroserpin), member 1, Serpin I1, PI-12, PI12, Ns, AI837402 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4G149 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human SERPINI1 in human brain with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| 应用 | ELISA,IHC-P |
| 推荐剂量 | ELISA: 1:1000-1:2000; IHC-P: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Neuroserpin / SerpinI1 (rh Neuroserpin / SerpinI1; TMPY-01241; NP_005016.1; Met1-Leu410). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Neuroserpin, also known as Protease inhibitor 12 and SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. Neuroserpin is predominantly expressed in the brain, and is expressed in the late stages of neurogenesis during the process of synapse formation. Overexpression of neuroserpin in an anterior pituitary corticotroph cell line results in the extension of neurite-like processes, suggesting that neuroserpin may play a role in cell communication, cell adhesion, and/or cell migration. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. Neuroserpin may also protect neurons from cell damage by tissue-type plasminogen activator. Defects of neuroserpin are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Neuroserpin / SerpinI1 Protein (TMPY-01241) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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