D-chiro-Inositol

Name: D-chiro-Inositol
Brand: TargetMol
SKU: T5915
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.76%

货号 T5915Cas号 643-12-9

别名 D-手性肌醇, D-(+)-CHIRO-INOSITOL

D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) 是肌醇差向异构体，存在于某些哺乳动物糖基磷脂酰肌醇蛋白锚和具有胰岛素样生物特性的肌醇磷脂聚糖中。它能够抑制高血糖，改善胰岛素抵抗。它用于多囊卵巢综合征和糖尿病的相关研究。

D-chiro-Inositol

一键复制产品信息

很棒

纯度: 99.76%

货号 T5915 别名 D-手性肌醇, D-(+)-CHIRO-INOSITOLCas号 643-12-9

规格	价格	库存	数量
50 mg	¥ 108	现货

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纯度: 99.76%

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产品介绍

D-chiro-Inositol AI Summary

D-chiro-Inositol exhibits diverse bioactivities with significant inhibitory and inductive properties. It functions as an inhibitor of the malarial parasite plastid with a potency of 7375.3 nM over a 96-hour incubation period and as an inhibitor of Polymerase Iota with a potency of 631.0 nM in a confirmatory assay. Additionally, it induces DNA re-replication in SW480 colon adenocarcinoma cells, achieving a potency of 231.1 nM in a high throughput screen assay. Moreover, D-chiro-Inositol significantly inhibits Baker's yeast Alpha-glucosidase-1 with an IC50 value of 1256100.0 nM, yet exhibits less than 30.0% inhibition of rat intestinal alpha-glucosidase maltase and sucrase when tested with maltose and sucrose, respectively. Furthermore, it induces glucose uptake in differentiated mouse 3T3L1 cells, increasing the uptake by 1.4-fold at 200 µM after 60 minutes and displaying 64.0% of the activity relative to insulin..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) is an epimer of myo-inositol that is found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity.
别名	D-手性肌醇, D-(+)-CHIRO-INOSITOL

化学信息

分子量	180.16
分子式	C₆H₁₂O₆
CAS No.	643-12-9
Smiles	O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
密度	2.038 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 75 mg/mL (416.3 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	5.5506 mL	27.7531 mL	55.5062 mL	277.5311 mL
5 mM	1.1101 mL	5.5506 mL	11.1012 mL	55.5062 mL
10 mM	0.5551 mL	2.7753 mL	5.5506 mL	27.7531 mL
20 mM	0.2775 mL	1.3877 mL	2.7753 mL	13.8766 mL
50 mM	0.1110 mL	0.5551 mL	1.1101 mL	5.5506 mL
100 mM	0.0555 mL	0.2775 mL	0.5551 mL	2.7753 mL