N-Benzyloctadecanamide

Name: N-Benzyloctadecanamide
Brand: TargetMol
SKU: T8120
Price: 993 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: N-苄基硬脂酰胺, N-Benzylstearamide

货号 T8120Cas号 5327-45-7 一键复制产品信息纯度: 97.01%

很棒

N-Benzyloctadecanamide 是一种 Macamide，Macamides 是Lepidium meyeniiWalp (玛咖)中的一类独特的次级代谢产物。

N-Benzyloctadecanamide

一键复制产品信息

很棒

纯度: 97.01%

货号 T8120Cas号 5327-45-7

别名 N-苄基硬脂酰胺, N-Benzylstearamide

N-Benzyloctadecanamide 是一种 Macamide，Macamides 是Lepidium meyeniiWalp (玛咖)中的一类独特的次级代谢产物。

规格	价格	库存
1 mg	¥ 993	现货
2 mg	¥ 1,490	现货
5 mg	¥ 2,570	现货
10 mg	¥ 4,130	现货
25 mg	¥ 6,490	现货

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纯度: 97.01%

颜色: 白色

性状: Solid

资源下载: COA LCMS HNMR产品操作手册

产品介绍

N-Benzyloctadecanamide AI Summary

N-Benzyloctadecanamide exhibits weak inhibition of human recombinant fatty acid amide hydrolase (FAAH) enzyme activity in vitro, with the highest observed inhibition being 26.2% at a 500 µM substrate concentration, and an IC50 value greater than 500,000 nM as determined using a fluorescence assay with N-arachidonyl-7-amino-4-methylcoumarin as the substrate. The compound also shows inhibitory activity against soluble epoxide hydrolase (sEH) in mice and rats, with IC50 values of 59,600 nM and 35,800 nM respectively, but demonstrates weaker inhibitory activity against human sEH with an IC50 value exceeding 100,000 nM. Additionally, N-Benzyloctadecanamide displays cytotoxic effects on human THP-1 cells with a CC50 value of 100,000 nM according to the MTT assay. The compound inhibits LPS-induced TNFalpha production in THP-1 cells with an IC50 of 16,600 nM after a 2-hour incubation, followed by LPS stimulation for 12 hours, as measured by ELISA. Overall, N-Benzyloctadecanamide demonstrates limited potency as a FAAH inhibitor and exhibits weak inhibition of both sEH and TNFalpha production..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	N-Benzyloctadecanamide is a distinct class of secondary metabolites in Lepidium meyenii Walp. (Maca).
别名	N-苄基硬脂酰胺, N-Benzylstearamide

化学信息

分子量	373.61
分子式	C₂₅H₄₃NO
CAS No.	5327-45-7
Smiles	CCCCCCCCCCCCCCCCCC(=O)NCc1ccccc1
密度	0.913g/cm3

储存&溶解度

存储

Keep away from moisture,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: Slightly soluble

计算器

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体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。