Prexasertib mesylate

Name: Prexasertib mesylate
Brand: TargetMol
SKU: T4310L2
Rating: 4.5 (1 reviews)

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产品编号 T4310L2Cas号 1234015-55-4

别名 LY-2606368, LY2606368, LY 2606368

Prexasertib is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 causes replication catastrophe and antitumor effects through CHK1-dependent mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population.

Prexasertib mesylate

还可以

产品编号 T4310L2 别名 LY-2606368, LY2606368, LY 2606368Cas号 1234015-55-4

规格	价格	库存
25 mg	¥ 10,600	1-2周
50 mg	¥ 13,800	1-2周
100 mg	¥ 17,500	1-2周

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产品描述	Prexasertib is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 causes replication catastrophe and antitumor effects through CHK1-dependent mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population.
靶点活性	Chk1:<1 nM (IC50), Chk1:0.9 nM (Ki), Chk2:8 nM (IC50)
别名	LY-2606368, LY2606368, LY 2606368