Name: FT113
Brand: TargetMol
SKU: T7947
Price: 527 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 527

现货

5 mg

¥ 990

现货

10 mg

¥ 1,590

现货

25 mg

¥ 2,730

现货

50 mg

¥ 3,830

现货

100 mg

¥ 5,170

现货

200 mg

¥ 6,960

现货

1 mL x 10 mM (in DMSO)

¥ 893

现货

产品介绍

生物活性

产品描述	FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
靶点活性	Fas:213 nM
体内活性	FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.Caused 32 % and 50% tumor growth inhibition at 25 and 50 mg/kg, respectively in mice.
动物实验	Athymic nude mice bearing MV-411 cells. Dosage:5, 25, or 50 mg/kg, twice daily for 16 days

化学信息

分子量	409.41
分子式	C₂₂H₂₀FN₃O₄
CAS No.	1630808-89-7
Smiles	OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1
密度	1.456 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 62.5 mg/mL (152.66 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.89 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

体内实验配液计算器