Tosufloxacin hydrochloride

Name: Tosufloxacin hydrochloride
Brand: TargetMol
SKU: T8835
Rating: 4.5 (1 reviews)

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纯度: 99.26%

货号 T8835Cas号 104051-69-6

别名 盐酸妥舒沙星, T-3262 hydrochloride, A-61827 hydrochloride

Tosufloxacin hydrochloride 是一种氟喹诺酮类抗菌剂，用于治疗细菌感染。 Tosufloxacin hydrochloride 也是一种细菌 Topo（DNA 促旋酶，拓扑异构酶）抑制剂。

Tosufloxacin hydrochloride

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纯度: 99.26%

货号 T8835 别名 盐酸妥舒沙星, T-3262 hydrochloride, A-61827 hydrochlorideCas号 104051-69-6

Tosufloxacin hydrochloride 是一种氟喹诺酮类抗菌剂，用于治疗细菌感染。 Tosufloxacin hydrochloride 也是一种细菌 Topo（DNA 促旋酶，拓扑异构酶）抑制剂。

规格	价格	库存
1 mg	¥ 142	待询
5 mg	¥ 287	待询
10 mg	¥ 438	待询
25 mg	¥ 793	待询
50 mg	¥ 1,260	待询
100 mg	¥ 1,980	待询
200 mg	¥ 3,300	待询

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纯度: 99.26%

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产品介绍

Tosufloxacin hydrochloride AI Summary

Tosufloxacin hydrochloride exhibits a wide range of bioactivities. It displays supercoiling inhibition activity on DNA gyrase from Escherichia coli H560 with an IC50 of 0.4 µg/mL. The compound also shows in vitro antimicrobial activity against various bacterial strains, including Staphylococcus aureus, Escherichia coli, Streptococcus, and Pseudomonas, with MIC values ranging from 0.01 to 6.2 µg/mL. In vivo studies indicate efficacy against Pseudomonas aeruginosa and Escherichia coli when administered subcutaneously or orally. Its solubility in different aqueous media varies from 1.2 to 23.5 µg/mL, depending on the pH and buffer type. However, Tosufloxacin hydrochloride shows low bioactivity in assays against SARS-CoV-2, with an inhibition index of 0.1095, indicating minimal inhibitory effects on the virus under the tested conditions..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Tosufloxacin hydrochloride is a fluoroquinolone antibacterial agent used to treat bacterial infections.Tosufloxacin hydrochloride is also a bacterial Topo (DNA gyrase, topoisomerase)) inhibitor.
别名	盐酸妥舒沙星, T-3262 hydrochloride, A-61827 hydrochloride

化学信息

分子量	440.8
分子式	C₁₉H₁₆ClF₃N₄O₃
CAS No.	104051-69-6
Smiles	FC1=CC(F)=C(N2C=C(C(O)=O)C(C3=C2N=C(N4CCC(N)C4)C(F)=C3)=O)C=C1.Cl
密度	no data available

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: Slightly soluble