Fmoc-Ala-Glu-Asn-Lys-NH2

Name: Fmoc-Ala-Glu-Asn-Lys-NH2
Brand: TargetMol
SKU: T38116
Rating: 4.5 (1 reviews)

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产品编号 T38116Cas号 220701-06-4

别名 Fmoc-Ala-Glu-Asn-Lys-NH2

Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a crucial role in the proteolytic processing of APP, and its activity is enhanced during the aging process [1].

Fmoc-Ala-Glu-Asn-Lys-NH2

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产品编号 T38116 别名 Fmoc-Ala-Glu-Asn-Lys-NH2Cas号 220701-06-4

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生物活性

产品描述	Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a crucial role in the proteolytic processing of APP, and its activity is enhanced during the aging process [1].
体外活性	Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].
别名	Fmoc-Ala-Glu-Asn-Lys-NH2

化学信息

分子量	681.747
分子式	C₃₃H₄₃N₇O₉
CAS No.	220701-06-4
Sequence Short	{Fmoc}-AENK-NH2

储存&溶解度

存储

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 100 mg/mL (146.68 mM), Sonication and heating to 80℃ are recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4668 mL	7.3341 mL	14.6682 mL	73.3410 mL
5 mM	0.2934 mL	1.4668 mL	2.9336 mL	14.6682 mL
10 mM	0.1467 mL	0.7334 mL	1.4668 mL	7.3341 mL
20 mM	0.0733 mL	0.3667 mL	0.7334 mL	3.6670 mL
50 mM	0.0293 mL	0.1467 mL	0.2934 mL	1.4668 mL
100 mM	0.0147 mL	0.0733 mL	0.1467 mL	0.7334 mL