Name: Anti-Mouse LAG-3 Antibody (C9B7W)
Brand: TargetMol
SKU: T78266
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 880

2-4周

5 mg

¥ 3,580

2-4周

10 mg

¥ 6,130

2-4周

生物活性

产品描述	Anti-Mouse LAG-3 Antibody (C9B7W) is a monoclonal antibody inhibitor targeting the D2 domain of mouse LAG-3 (CD223). It blocks LAG-3 dimerisation and the interactions between LAG-3 and FGL1, LSECtin, and α-synuclein. It does not affect MHCII/LAG-3 interactions, thereby enhancing T-cell proliferation and antitumour effects, making it suitable for tumour immunotherapy.
体内活性	方法：Anti-Mouse LAG-3 Antibody (C9B7W) （10mg/kg，联合 PD-1 mAb，腹腔注射，每 3 天一次，连续 14 和 21 天）处理Nitrochin (100 µg/mL) 诱导的 C57BL/6 小鼠，研究其对小鼠体内肿瘤的影响。结果：Anti-Mouse LAG-3 Antibody (C9B7W) 能使57.1% 的小鼠肿瘤生长被抑制。[1]
克隆号	C9B7W
反应种属	Mouse
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
内毒素	＜ 1.0 EU/mg