Pterostilbene

Name: Pterostilbene
Brand: TargetMol
SKU: T2888
Price: 250 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.20%

货号 T2888Cas号 537-42-8

别名 紫檀茋, 紫檀芪

Pterostilbene 是从蓝莓和囊状紫檀中得到的一种芪类天然产物，可抑制 ROS 的生成，能对抗多种自由基，具有抗氧化、抗炎、抗癌、抗糖尿病和抗肥胖等作用。

Pterostilbene

一键复制产品信息

很棒

纯度: 99.20%

货号 T2888 别名 紫檀茋, 紫檀芪Cas号 537-42-8

规格	价格	库存	数量
20 mg	¥ 330	现货
1 mL x 10 mM (in DMSO)	¥ 250	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.20%

联系我们获取更多批次信息

资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

Pterostilbene AI Summary

Pterostilbene exhibits a broad range of bioactivities, including significant antiproliferative and proapoptotic activities against various human and mouse cancer cell lines. Specifically, it inhibits the proliferation of human HL60 cells with an IC50 of 35000 nM and induces apoptosis in these cells at a concentration of 70000 nM. It also shows potent cytotoxicity against human MDA-MB-231 cells (IC50 of 10000 nM) and demonstrates inhibitory effects on cell lines like HT1080, PANC1, A549, and HeLa with IC50 values in the nanomolar range. Furthermore, it significantly inhibits amyloid beta 25-35 fibril formation (35% inhibition at 10 μM), COX1 and COX2 enzymes (IC50 values of 700 nM and 820 nM, respectively), and has observable antihyperglycemic activity in diabetic rats. Additionally, Pterostilbene modulates various molecular pathways, including inhibiting Rac1 and uPA activities in MDA-MB-231 cells, showing antioxidant and antifungal activities, and demonstrating anti-inflammatory effects in mouse J774 cells. It also exhibits significant bactericidal activity against methicillin-resistant Staphylococcus aureus and shows antiviral activity against SARS-CoV-2. With a log P value of 3.15 and an oral bioavailability of 80% in rats, Pterostilbene appears to be highly lipophilic and bioavailable, making it a compound of interest for further pharmacological studies..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Pterostilbene is extracted from Pterocarpus indicus.
别名	紫檀茋, 紫檀芪

化学信息

分子量	256.30
分子式	C₁₆H₁₆O₃
CAS No.	537-42-8
Smiles	C(=C/C1=CC=C(O)C=C1)\C2=CC(OC)=CC(OC)=C2
密度	1.169 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 200 mg/mL (780.34 mM), Sonication is recommended.

体内实验配方

5% DMSO+40% PEG300+5% Tween 80+50% Saline: 9.00 mg/mL (35.12 mM), Suspension.

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.30 mg/mL (12.88 mM), Sonication is recommended.

50% PEG300+50% Saline: 10.00 mg/mL (39.02 mM)

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9017 mL	19.5084 mL	39.0168 mL	195.0839 mL
5 mM	0.7803 mL	3.9017 mL	7.8034 mL	39.0168 mL
10 mM	0.3902 mL	1.9508 mL	3.9017 mL	19.5084 mL
20 mM	0.1951 mL	0.9754 mL	1.9508 mL	9.7542 mL
50 mM	0.0780 mL	0.3902 mL	0.7803 mL	3.9017 mL
100 mM	0.0390 mL	0.1951 mL	0.3902 mL	1.9508 mL