10000+
1000+
51
49
13176
Cat. No. | Product Name | ||
---|---|---|---|
L6160 | Ro5类药天然产物库 | 2703 compounds | |
2703 种符合 RO5原则的天然产物单体集合,可以用于高通量和高内涵筛选; | |||
L1000 | 上市药物库 | 2808 compounds | |
2808 个上市药物化合物集合,可用于高通量筛选和高内涵筛选; | |||
L6120 | 黄酮类天然产物库 | 477 compounds | |
477 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1020 | EMA 上市药物库 | 657 compounds | |
657个EMA批准药物的独特集合,可用于高通量筛选和高内涵筛选 | |||
L1100 | 蛋白酶抑制剂库 | 343 compounds | |
343 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选; | |||
L2110 | 抗癌上市药物库 | 1779 compounds | |
1779 个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA 或NMPA 批准上市,可用于高通量、高内涵筛选。 | |||
L2200 | 酪氨酸激酶分子库 | 1016 compounds | |
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6130 | 萜类天然产物库 | 516 compounds | |
516 种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L8110 | 细胞重编程化合物库 | 1813 compounds | |
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选 | |||
L6900 | 稀有天然产物库 | 178 compounds | |
178 种稀有天然产物的集合,可以用于高通量和高内涵筛选; | |||
L7860 | Mini片段亲电杂环化合物库 | 369 compounds | |
高溶解度共价杂环片段库中的 369 个化合物 | |||
L7810 | 高溶解性多官能团片段化合物库 | 1159 compounds | |
高溶解性多官能团片段库包含1159 种片段分子 | |||
L6001 | Mini真菌代谢天然产物筛选库 | Inquiry | |
L1010 | FDA上市及药典收录分子库 | 3157 compounds | |
3157 个上市及药典分子集合,可用于高通量筛选和高内涵筛选; | |||
L1520 | 膜蛋白靶向化合物库 | 4229 compounds | |
L5100 | 含氟化合物库 | 574 compounds | |
574 个含氟化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L6100 | 天然多酚类化合物库 | 635 compounds | |
635 个天然多酚化合物的独特集合,可用于高通量、高内涵筛选; | |||
L6620 | 抗寄生虫天然产物库 | 253 compounds | |
253 个抗寄生虫相关的天然产物集合,是药物开发、药理研究的有效工具; | |||
L6610 | 抗感染天然产物库 | 1060 compounds | |
1060 个抗感染相关的天然产物集合,是药物开发、药理研究的有效工具; | |||
L4210 | NMPA中国上市药物库 | 1270 compounds | |
1270 个 NMPA 中国上市药物的独特集合,可用于高通量筛选和高内涵筛选; | |||
NY1000 | 天然产物衍生物库 | 4000 compounds | |
22个天然产物骨架,3745个天然产物衍生物; | |||
L4200 | FDA 上市药物库 | 1729 compounds | |
1729 个FDA 批准药物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L6110 | 生物碱类天然产物库 | 464 compounds | |
464 种生物碱类天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6800 | 中国药典收录天然产物库 | 2051 compounds | |
2051 种中国药典收录的天然产物,是药物开发、药理研究等领域的有力工具; | |||
L6700 | 抗癌天然产物库 | 1772 compounds | |
1772 种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS 和HCS。 | |||
L6150 | 天然产物共价化合物库 | 583 compounds | |
提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础; | |||
L9300 | 大环化合物库 | 210 compounds | |
210 种活性已知的大环化合物,用于高通量、高内涵筛选; | |||
L2630 | 神经元分化化合物库 | 672 compounds | |
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发 | |||
L2195 | 抗前列腺癌化合物库 | 2070 compounds | |
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选 | |||
L6000 | 高通量筛选天然产物库 | 4441 compounds | |
4441 种天然产物的独特集合,是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具,可用于HTS 和HCS; | |||
L2540 | 肠道微生物代谢化合物库 | 607 compounds | |
607 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; | |||
L2600 | 神经信号分子库 | 2540 compounds | |
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2620 | 神经退行性疾病化合物库 | 2154 compounds | |
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选; | |||
L6140 | 糖类及苷类化合物库 | 362 compounds | |
362 种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选; | |||
L8710 | 铜死亡化合物库 | 400 compounds | |
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究 | |||
L9810 | 抗纤维化化合物库 | 1155 compounds | |
1155 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选; | |||
L8720 | 细胞焦亡化合物库 | 1066 compounds | |
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。 | |||
L6020 | 天然产物单体化合物库 | 16627 compounds | |
16627 种精选天然产物集合,结构多样,遍布多种动植物与微生物; | |||
L6030 | 天然产物衍生物虚筛化合物库 | 163000 compounds | |
16.3万种天然产物衍生物,并且在持续增加中; | |||
L2610 | 神经递质受体化合物库 | 1513 compounds | |
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选; | |||
L2800 | 5-羟色胺分子库 | 268 compounds | |
268 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L6010 | 天然产物库 | 3685 compounds | |
3685 种天然产物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L4710 | 非甾体类抗炎化合物库 | 521 compounds | |
521 种非甾体类的抗炎相关化合物,可用于高通量和高内涵筛选; | |||
L6500 | 微生物天然产物库 | 550 compounds | |
550 种微生物来源的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L7820 | 高溶解性微型片段化合物库 | 1081 compounds | |
高溶解性微型片段化合物库由 1081 个低分子量片段组成。 | |||
L8700 | 铁死亡化合物库 | 779 compounds | |
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选; | |||
L8300 | 染色质修饰分子库 | 250 compounds | |
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8720 | 细胞焦亡化合物库 | 1066 compounds | |
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28589 |
Ro 41-5253
Ro-41-5253,Ro 415253 |
Apoptosis; Retinoid Receptor | Apoptosis; Metabolism |
Ro 41-5253 是一种具有口服活性的 RARα 拮抗剂,是过氧化物酶体增殖物激活受体 (PPAR)-γ 的配体和部分激动剂,具有抗肿瘤活性,抑制 MCF-7 和 ZR-75.1 雌激素受体阳性乳腺癌细胞的增殖并诱导细胞凋亡。 | |||
T16773 |
Ro 90-7501
RO-90-7501 |
Apoptosis; Phosphatase; ATM/ATR; Gamma-secretase | Apoptosis; DNA Damage/DNA Repair; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Ro 90-7501 是一种淀粉样 β42 (Aβ42) 原纤维和 TPR 依赖性 PP5 抑制剂,是一种新型宫颈癌细胞放射增敏剂,可抑制 ATM 磷酸化 ,促进细胞凋亡,诱导细胞周期停滞。Ro 90-7501 具有抗病毒活性和潜在的抗癌活性,抑制 ATM 磷酸化和 DNA 修复,抑制HCMV。 | |||
T6643 |
Ro 31-8220 Mesylate
Ro 31-8220 methanesulfonate,Bisindolylmaleimide IX,Bisindolylmaleimide IX mesylate |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) 是PKC 抑制剂,对 PKCα、PKCβI、PKCβII、PKCγ、PKCε 和大鼠大脑 PKC 的IC50值为 5、24、14、27、24 和 23 nM。它还抑制 MAPKAP-K1b、MSK1、S6K1 和 GSK3β,IC50为3、8、15 和 38 nM。 | |||
T16771 |
RO-5963
|
Mdm2; p53 | Apoptosis |
RO-5963是p53-MDM2和p53-MDMX 的双重抑制剂(IC50s:~17nM 和~24nM)。 | |||
T2356 |
Ro-3306
|
Apoptosis; ERK; SGK; PKA; CDK; PKC | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors |
Ro 3306 是一种选择性 ATP 竞争性CDK1抑制剂,对 CDK1、CDK1/cyclin B1 和 CDK2/cyclin E 的Ki 值为分别为 20 nM、35 nM 和 340 nM。 | |||
T5513 |
RO-3
|
P2X Receptor | Membrane transporter/Ion channel; Neuroscience |
RO3 是一种能透过大脑的P2X3和P2X2/3拮抗剂,口服有活性。它对人同型多聚体 P2X3和异型多聚体 P2X2/3受体的 pIC50分别为 5.9 和 7.0。 | |||
T9223 |
RO-0335
|
Reverse Transcriptase | Microbiology/Virology |
RO-0335 是新高效二苯醚非核苷逆转录酶抑制剂。它 (IC50= 1.1 nM) 可以抑制Wt HIV-1病毒,对 92% 的 NNRTI 耐药临床分离株具有保留活性 (IC50<100 nM)。 | |||
T6971 |
Ro 5126766
CH5126766,Avutometinib,VS-6766,RO5126766 |
Raf; MEK | MAPK |
Ro 5126766 (CH5126766) 是双重MEK/RAF 抑制剂,抑制BRAFV600E、CRAF、MEK 和 BRAF,IC50分别为 8.2、56、160 和 190 nM。 | |||
T12758 |
Ro 25-6981
|
NMDAR | Neuroscience |
Ro 25-6981 是一种有效的选择性活性依赖性 NMDA 受体阻滞剂,含有 NR2B 亚基,对克隆受体亚基组合 NR1C/NR2B 和 NR1C/NR2A 的 IC50 分别为 0.009 和 52 μM。 Ro 25-6981 可用于帕金森病的研究。 | |||
T34373 |
RO5166017
RO 5166017,RO-5166017 |
Others | Others |
RO5166017 是一种具有口服活性、高效性和选择性的痕量胺相关受体 1(TAAR1)激动剂,可用于研究条件性味觉厌恶额神经障碍。 | |||
T16766 |
Ro 08-2750
|
||
Ro 08-2750 是一种非肽和可逆的神经生长因子 (NGF) 抑制剂,与 NGF 结合,IC50 约为 1 µM。它是一种选择性 MSI RNA 结合活性抑制剂,IC50 为 2.7 μM。它选择性抑制 NGF 与 p75NTR 的结合,而不是 TRKA。 | |||
T3194 |
Ro 46-2005
|
Endothelin Receptor | GPCR/G Protein |
Ro 46-2005是新型非肽类内皮素拮抗剂,能够抑制人血管平滑肌细胞(ETA 受体)(IC50:220 nM)。 | |||
T1896 |
Ro 61-8048
|
Hydroxylase | Metabolism |
Ro 61-8048 是一种选择性的、口服有效的犬尿氨酸 3-羟化酶抑制剂(IC50:37 nM)。它能够导致细胞喹啉酸浓度的显著增加。 | |||
T3474 |
RO 46-8443
|
Endothelin Receptor | GPCR/G Protein |
Ro 46-844 是选择性非肽内皮素受体拮抗剂。它对ETB(IC50: 34-69 nM) 的选择性比ETA 受体 (IC50: 6800 nM) 高的100倍以上。 | |||
T28578 |
Ro24-7429
Ro 24-7429,Ro-24-7429,Ro 247429 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Ro24-7429 是一种有效的口服活性 HIV-1 反式激活蛋白 Tat 拮抗剂和一种矮小相关转录因子 1 的抑制剂。Ro24-7429 具有抗 HIV、抗纤维化和抗炎作用。 | |||
T9021 |
Ro0711401
Ro-0711401,Ro 0711401 |
GluR | Neuroscience |
Ro0711401 是一种可口服的 mGlu1受体选择性正变构调节剂,EC50为 56 nM。 | |||
T3478 |
Ro 67-7476
|
GluR | Neuroscience |
Ro 67-7476 是mGluR1的正变位调节剂,能增强表达 rat mGluR1a 的 HEK293 细胞中谷氨酸诱导的钙释放,EC50为 60.1 nM。它是 P-ERK1/2 激动剂,可以在外源添加谷氨酸的情况下激活 ERK1/2 磷酸化 (EC50=163.3 nM)。 | |||
T1771 |
Ro 48-8071 fumarate
|
Others | Others |
Ro 48-8071 fumarate 是一种氧化鲨烯环化酶抑制剂(IC50:6.5 nM)。 | |||
T9357 |
Ro 5212773
Epptb |
Others | Others |
Ro 5212773 (Epptb) 是TAAR1的选择性拮抗剂(对于小鼠 TAAR1 的Ki= 0.9 nM),对其他 TAARs 没有显著影响。其中TAAR1 是一种 G 蛋白偶联受体 (GPCR),能够被内源性氨基酸代谢产物非选择性的激活。 | |||
T12761 |
Ro 10-5824 dihydrochloride
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Ro 10-5824 dihydrochloride 是选择性的多巴胺D4 受体部分激动剂,Ki=5.2 nM。 | |||
T2634 |
Ro3280
RO 3280,Ro5203280 |
PLK | Cell Cycle/Checkpoint |
Ro3280 (Ro5203280) 是一种高度选择性的PLK1抑制剂,IC50和Kd 值分别为 3 nM 和 0.09 nM。 | |||
T34374 |
RO5203648 HCl
RO5203648,RO-5203648,RO 5203648 |
Others | Others |
RO5203648 HCl 是一种微量胺相关受体 1 (TAAR1) 的部分激动剂,具有抗精神病和抗抑郁样活性。 RO5203648 HCl 可用于神经精神治疗的研究。 | |||
T4141 |
RG7713
RO 5028442 |
Vasopressin Receptor | GPCR/G Protein |
RG7713 (RO 5028442) 是一种高效且有选择性的脑-渗透加压素 1a (V1a) 受体拮抗剂,对人类 (hV1a) 和小鼠 (mV1a) 受体的 Ki 值分别为 1 和 39 nM,可用于研究自闭症的试验。 | |||
T4687 |
Ro5-3335
CBFβ-Runx1 inhibitor II,Ro 5-3335 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Ro5-3335 (CBFβ-Runx1 inhibitor II) 是苯二氮化合物,是RUNX1-CBFβ 相互作用抑制剂,可抑制 RUNX1/CBFB 依赖性反式激活,能作为核心结合因子 (CBF) 白血病抑制剂。 | |||
T36716 |
RO0270608
RO0270608 |
||
RO0270608, the active metabolite of R411, is a dual α4β1/α4β7 integrin antagonist with anti-inflammatory activity[1][2]. | |||
T68134 |
Ro-3201195
|
p38 MAPK | MAPK |
Ro-3201195是一种新型可口服的p38 MAPK 抑制剂,具有很高的选择性。 | |||
T69360 |
RO3244794
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
RO3244794是一种具有选择性的前列环素 (IP)受体拮抗剂,可用于研究肝脏损伤。 | |||
T39702 |
RO7185876
|
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
RO7185876 是一种具有选择性的γ 分泌酶调节剂,可用于研究阿尔茨海默病。 | |||
T27838 |
Lirequinil
RO413696,RO-413696,RO41-3696,RO 413696,Ro 41-3696,Ro-41-3696 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Lirequinil (Ro 41-3696) 是一种小分子 GABAA 受体激动剂,可用于研究神经系统疾病。 | |||
T12745 |
RO5263397
|
Others | Others |
RO5263397是一种 TAAR1特异性激动剂,具有口服活性,被用于抗抑郁研究。它还被发现作为环氧化酶-2 (COX-2)的抑制剂,参与前列腺素的合成。 | |||
T27399 |
Galocitabine
RO 091390,RO-091390,RO091390,RO-09-1390,Neofrutulon |
Others | Others |
Galocitabine (Neofrutulon) 是一种胸苷酸合成酶抑制剂,可能用于治疗癌症。 | |||
T68104 |
Mofarotene
Ro-40-8757,Ro 40-8757 |
Retinoid Receptor | Metabolism |
Mofarotene (Ro-40-8757) 是一种小分子化合物,在许多癌细胞系中显示出相当大的抗肿瘤活性,可用于治疗肿瘤和呼吸系统疾病。Mofarotene 是一种维甲酸类似物,可结合并激活维甲酸受体(RARs),从而改变某些基因的表达,导致易感细胞的细胞分化和细胞增殖降低。 | |||
T16776 |
RO9021
|
Syk | Angiogenesis; Tyrosine Kinase/Adaptors |
RO9021 是口服具有活力的,ATP 竞争性的 SYK 抑制剂,其 IC50=5.6 nM。 | |||
T9054 |
RO6889678
|
HBV | Microbiology/Virology |
RO6889678 是高效的 HBV 衣壳结构抑制剂,其吸收、分布、代谢和排泄特征较为复杂。它可通过 CYP3A4 介导的氧化作用进行代谢,以及通过 UDP-葡萄糖醛酸基转移酶 UGT1A3 和 UGT1A1 介导的直接葡萄糖醛酸化作用进行代谢。它是一种诱导剂,可作用于人肝细胞中 CYP3A4 和共调节蛋白。 | |||
T4436 |
RO1138452
CAY10441 |
Others; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Others |
RO1138452 (CAY10441) 是一种选择性和可口服的前列环素受体拮抗剂,pKi 为8.3。它拮抗卡前列环素诱导的人神经母细胞瘤腺苷酸环化酶的激活,以剂量依赖性方式阻断环 AMP 积累,具有镇痛活性。 | |||
T23245 |
Ro-51
Ro 51 |
Others | Others |
dual P2X3 and P2X2/3 antagonist | |||
T22142 |
RO8191
RO4948191,CDM-3008 |
HCV Protease; HBV; JAK; IFNAR; STAT | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合,激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用,并具有抗 HBV 活性。 | |||
T8447 |
Ro 8-4304
Ro 8-4304 Hydrochloride |
NMDAR | Neuroscience |
Ro 8-4304 Hydrochloride 是 NMDA 受体的拮抗剂,IC50 为 0.4 μM。 | |||
T28595 |
Ro-0505124
Ro0505124,Ro 0505124 |
||
Ro-0505124 is a potent, selective and ATP-competitive inhibitor of cyclin-dependent kinase 4 (CDK4). | |||
T22416 |
RO495
CS-2667 |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
RO495 (CS-2667) 是一种有效的非受体酪氨酸蛋白激酶2抑制剂。 | |||
T17034 |
Temarotene
Ro 15-0778 |
Others | Others |
Temarotene(Ro 15-0778) 是一种具有口服活性和有效性的小分子化合物,可在体外调节人体免疫功能。Temarotene 可用于研究扁平苔藓。 | |||
T34347 |
Ro 12-9150
Ro-129150,Ro-12-9150 |
||
Ro 12-9150 is a bio-active agent. | |||
T28571 |
RO 23-6152
RO 236152,RO-23-6152 |
||
RO 23-6152, a new calcium antagonist, can inhibit platelet aggregation in vitro associated with occlusive coronary thrombus formation. | |||
T34362 |
Ro 47-1669
Ro 471669,Ro-47-1669 |
||
Ro 47-1669 is a bioactive chemical. | |||
T28588 |
Ro 41-1879
Ro-41-1879,Ro 411879 |
||
Ro 41-1879 is a catechol cephalosporin with antimicrobial activity. | |||
T28557 |
Ro 14-9578
Ro-14-9578,Ro 149578 |
||
Ro 14-9578 is anantibacterial agent in the class of tricyclic quinolone. | |||
T28586 |
Ro 31-8830
Ro-31-8830,Ro 318830 |
||
Ro 31-8830, a derivative of Ro 31-8425, has in vivo anti-inflammatory activity. | |||
T34364 |
Ro 5-6669
Ro-5-6669,Ro 56669 |
||
Ro 5-6669 is bioactive chemical. | |||
T28566 |
Ro 22-8515
Ro 228515,Ro-22-8515 |
||
Ro 22-8515 is the ligand of benzodiazepine receptor. | |||
T34357 |
Ro 31-0313
Ro 310313,Ro-31-0313 |
||
Ro 31-0313 is a metabolite of Ro 03-8799, radiation sensitizing agent. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3915 |
Ginsenoside Ro
人参皂苷Ro,Chikusetsusaponin 5,Polysciasaponin P3,人参皂苷 Ro,Chikusetsusaponin V |
Calcium Channel; Reductase; Prostaglandin Receptor | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism |
Ginsenoside Ro (Chikusetsusaponin V) 能降低 TXA2产量,较弱降低 COX-1 和 TXAS 活性,具有 Ca2+拮抗剂的抗血小板作用,IC50为 155 μM。 | |||
T28551 |
Ro 09-0680
Ro 09 0680,Ro-09-0680 |
||
Ro 09-0680 is an inhibitor of platelet aggregation. | |||
T1330 |
Acitretin
阿曲汀,Ro 10-1670,Etretin |
Apoptosis; Retinoid Receptor; Autophagy | Apoptosis; Autophagy; Metabolism |
Acitretin (Ro 10-1670) 是一种维甲酸,可用于银屑病和阿尔兹海默症的研究。 | |||
T1589 |
D-Cycloserine
RO-1-9213,D-环丝氨酸 |
Others; Antibacterial; Antibiotic; iGluR | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others |
D-Cycloserine (RO-1-9213) 是一种抗生素,靶向细菌细胞壁肽聚糖生物合成酶。它是一种NMDA 部分激动剂,可以改善认知功能,可研究耐多药结核病。 | |||
T1468 |
Lornoxicam
Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康 |
COX; Endogenous Metabolite | Immunology/Inflammation; Metabolism; Neuroscience |
Lornoxicam (Chlortenoxicam) 是一种新型非甾体抗炎药,是高活性 COX-1 和 COX-2 抑制剂,IC50 分别为 5 和 8 nM。 | |||
T1556 |
Ornidazole
Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑 |
Antibacterial; Antibiotic; Parasite | Microbiology/Virology |
Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物,能抗原生动物和厌氧菌。 | |||
T0986 |
Flucytosine
5-Fluorocytosine,Ro 2-9915,5-氟胞嘧啶,Fluorocytosine,NSC 103805 |
DNA/RNA Synthesis; Antibiotic; Antifungal | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Flucytosine (NSC 103805) 是抗真菌化合物。 | |||
T6430 |
Calcifediol
25-羟基维生素 D3,U 32070E,25-hydroxy Vitamin D3,RO 8-8892,骨化二醇 |
Endogenous Metabolite | Metabolism |
Calcifediol (U 32070E) 是由维生素 D3 在肝中经羟基化后得到的前激素,是 VDR 的有效抑制剂。 | |||
T6402 |
Azomycin
2-Nitroimidazole,2-硝基咪唑,Ro 05-9129,Amicin |
Antibacterial; Antibiotic | Microbiology/Virology |
Azomycin (Ro 05-9129) 是一种可抑制有氧革兰氏阳性菌和革兰氏阴性菌的生长的抗生素。 | |||
T6316 |
Calcitriol
Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3 |
Endogenous Metabolite | Metabolism |
Calcitriol (1,25-Dihydroxyvitamin D3) 是一种维他命 D 的代谢物,一种维他命 D 受体 (VDR) 的激动剂 (IC50=0.4 nM)。Calcitriol 增加肠道对钙和磷的吸收,并与甲状旁腺激素一起增加了骨吸收。 | |||
TQ0262 |
Dihomo-γ-linolenic acid
Diroleuton,顺式-8,11,14-二十烷三烯酸甲酯,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989 |
Others | Others |
Ro 12-1989 can be converted into prostaglandin E1 (PGE1). Ro 12-1989 competes with arachidonic acid for COX and lipoxygenase, inhibiting the production of arachidonic acid's eicosanoids. | |||
T2P2919 |
(2S,3R,4S)-4-Hydroxyisoleucine
(4S)-4-Hydroxy-L-isoleucine,(4S)4-羟基异亮氨酸,Hydroxyisoleucine |
PI3K | PI3K/Akt/mTOR signaling |
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) 是分离自胡芦巴中的一种可口服的有效成分,具有抗糖尿病、抗糖尿病肾病的作用。 | |||
T8130 |
Ciprofloxacin hydrochloride monohydrate
Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan |
Antibacterial; Antibiotic | Microbiology/Virology |
Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) 是一种具有高效抗菌活性的氟喹诺酮类抗生素。 | |||
T5915 |
D-chiro-Inositol
D-手性肌醇,D-(+)-CHIRO-INOSITOL |
Endogenous Metabolite | Metabolism |
D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) 是肌醇差向异构体,存在于某些哺乳动物糖基磷脂酰肌醇蛋白锚和具有胰岛素样生物特性的肌醇磷脂聚糖中。它能够抑制高血糖,改善胰岛素抵抗。它用于多囊卵巢综合征和糖尿病的相关研究。 | |||
T11590 |
(-)-Hydroxycitric acid
Garcinia acid,(-)-羟基柠檬酸 |
ATP Citrate Lyase | Metabolism |
(-)-Hydroxycitric acid (Garcinia acid) 是Garcinia cambogia 果皮中的主要酸。它是 ATP 柠檬酸裂解酶的竞争性抑制剂,能够抑制脂肪酸的合成,减少脂肪生成,控制食物摄入,从而减轻体重。 | |||
T2A2524 |
2-Hydroxy-4-methoxybenzaldehyde
4-甲氧基水杨醛,4-Methoxysalicylaldehyde,2-羟基-4-甲氧基苯甲醛 |
Tyrosinase; Antibacterial | Microbiology/Virology; Proteases/Proteasome |
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) 是一种来自三种东非药用植物,Mondia whitei、Rhus vulgaris Meikle 和Sclerocarya caffra Sond 的酪氨酸酶抑制剂。它是香兰素的异构体,可用于合成尿苷M7。 | |||
T4950 |
1,2-Dipalmitoyl-sn-glycerol
1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin |
Endogenous Metabolite; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism |
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) 是内源性代谢产物的一种。 | |||
T4768 |
Diethyl oxalpropionate
草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE |
Others; Endogenous Metabolite | Metabolism; Others |
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。 | |||
T21665 |
DL-α-Hydroxyglutaric acid disodium salt
disodium 2-hydroxypentanedioate,DL-Α-羟基戊二酸二钠 |
Others | Others |
DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) 是一种 α-羟基酸,由 (R) -5-oxy-2-tetrahydrofuran 羧酸水解形成,在人类神经代谢疾病 D-α-羟基戊二酸尿症中过量产生。 | |||
T0532 |
5,6-Dihydro-5-methyluracil
5, 6-Dihydrothymine,二氢朐腺嘧啶,Dihydrothymine |
Nucleoside Antimetabolite/Analog; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
5,6-Dihydro-5-methyluracil (Dihydrothymine) 是胸腺嘧啶的中间代谢产物之一,来源于动植物,浓度过高时会产生毒性。 | |||
T16542 |
Piromidic acid
吡咯酸,吡乙酸三氮萘 |
Antibacterial; Antibiotic | Microbiology/Virology |
Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性,可研究肠道,泌尿和胆道感染。 | |||
T8185 |
(+)-Viroallosecurinine
别一叶萩碱,Viroallosecurinine |
Antibacterial | Microbiology/Virology |
(+)-Viroallosecurinine (Viroallosecurinine) 是一种具有抗菌活性的天然生物碱,抑制Ps. Aeruginosa 和Staph. aureus,MIC 为 0.48 μg/mL。 | |||
T8084 |
Dimethyl 4-hydroxyisophthalate
二甲基 4-羟基异邻苯二甲酸酯,Dimetghyl 4-Hydroxyisophthalate |
Others | Others |
Dimethyl 4-hydroxyisophthalate (Dimetghyl 4-Hydroxyisophthalate) 是水杨酸甲酯类似物。 | |||
T7479 |
Ambroxide
降龙涎香醚,(-)-Ambroxide |
Others | Others |
Ambroxide ((-)-Ambroxide) 是龙涎香的一种关键成分,是天然存在的萜类化合物。 | |||
T8009 |
1-Furfurylpyrrole
1-(2-呋喃基甲基)-1H-吡咯,1-Furfurylpyrrole |
Others | Others |
1-Furfurylpyrrole 是一种潜在的爆米花香气的来源因素。 | |||
TN6780 |
Carvacrol methyl ether
Methyl carvacrol,Methyl carvacryl ether |
Antibacterial | Microbiology/Virology |
Carvacrol methyl ether 来源于植物挥发油,具有抗菌活性。 | |||
TN1957 |
Mulberrofuran Q
MulberrofuranQ |
||
Mulberrofuran Q是一种有活性的化合物,可抑制12-羟基-5,8,10-十七碳三烯酸(HHT)和血栓烷B2(环加氧酶产物)的形成 ,可保护神经细胞免受缺氧-缺糖(OGD)诱导的氧化应激的影响。 | |||
T8948 |
Ferroheme
protoheme,Hematin,heme |
Others | Others |
Ferroheme (protoheme) 是一种亚铁离子和卟啉的复合物,也是脂肪酸结合大鼠肝脏脂肪酸结合蛋白的同位异构抑制剂。 | |||
T5285 |
3-(Methylthio)propionic acid
3-Methylthiopropionate,3-甲基硫代丙酸,4-Thiapentanoic acid,3-Methylsulfanylpropionic acid |
Others; Endogenous Metabolite; Antifungal | Metabolism; Microbiology/Virology; Others |
3-(Methylthio)propionic acid (4-Thiapentanoic acid) 是methionine 的代谢物,是中间体。 | |||
T11589 |
Hydroxycitric acid tripotassium hydrate
柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate |
ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF | Angiogenesis; Chromatin/Epigenetic; Metabolism |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分,也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ,并具有减肥作用。它有效抑制结石形成,并抑制HIF,具有抗氧化,抗炎和抗肿瘤活性。 | |||
T5297 |
3-Indolepropionic acid
Indolepropionic acid,IPA,indole-3-propionic acid,吲哚-3-丙酸 |
Antioxidant; Reactive Oxygen Species; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
3-Indolepropionic acid (Indolepropionic acid) 是强效的抗氧化剂,具有研究阿尔兹海默症的潜能。 | |||
T20488 |
4-Isopropylbenzoic acid
NSC1907,NSC-1907,NSC 1907,Cumic acid |
Antifungal | Microbiology/Virology |
4-Isopropylbenzoic acid (Cumic acid) 是一种芳香单萜,从 Bridelia retusa 的茎皮中分离得到。4-Isopropylbenzoic acid 显示出抗真菌活性。4-Isopropylbenzoic acid 也是一种可逆的、非竞争性的蘑菇酪氨酸酶 (mushroom tyrosinase) 抑制剂。 | |||
T4727 |
Taurolithocholic acid sodium salt
牛磺石胆酸钠,Sodium taurolithocholate |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) 是抑胆剂和 Ca2+激动剂,可抑制放射性配体与毒蕈碱 M1 结合。 | |||
T3O2709 |
Bronze Red
808猩红,Scarlet 808 |
Others | Others |
Bronze Red 属于酰胺类有机物,可用于含量测定、鉴定、药理实验等。 | |||
TN4171 |
Grossamide
|
NO Synthase | Immunology/Inflammation |
Grossamide (GSE) 是一种来自虎杖的木脂酰胺。Grossamide 具有抗炎症活性,可通过上调精氨酸酶和下调诱导型一氧化氮合酶来抑制精氨酸产生一氧化氮(NO),抑制NO对OXPHOS的抑制作用。 | |||
T2S2018 |
7beta-Hydroxylathyrol
7β-Hydroxylathyrol,7-Hydroxylathyrol,7-beta-Hydroxylathyrol,7-羟基千金子二萜醇 |
P-gp | Membrane transporter/Ion channel; Neuroscience |
7β-Hydroxylathyrol 是天然萜类化合物的一种。 | |||
T8029 |
1-Methylpyrrolidine
|
Others | Others |
1-Methylpyrrolidine 是一种甲基化吡咯烷。 | |||
T8712 |
1-Palmitoyl-sn-glycero-3-phosphocholine
1-十六酰-SN-丙三醇-磷酸胆碱,1-Hexadecanoyl-sn-glycero-3-phosphocholine |
Others | Others |
1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) 是一种用于荧光探针设计的磷酸胆碱。 | |||
T5662 |
5-Hydroxy-1-tetralone
|
Others | Others |
5-hydroxy-1-tetralone 是一种荧光标记试剂,可用于生物样品中的鞘糖脂的测定。 | |||
T5004 |
Hyaluronic acid sodium
透明质酸钠,Sodium Hyaluronate |
Others | Others |
Hyaluronic acid sodium (Sodium Hyaluronate) 是一种生物聚合物,由二糖的重复单元组成,应用领域广泛。 | |||
T4814 |
(R)-5-Oxopyrrolidine-2-carboxylic acid
D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) 是内源性代谢产物的一种。 | |||
T5682 |
6-Hydroxyindole
|
Others | Others |
6-Hydroxyindole 是白色至浅棕色结晶或结晶性粉末。 | |||
TQ0024 |
3-Hydroxyglutaric acid
|
Endogenous Metabolite | Metabolism |
3-Hydroxyglutaric acid 是一种戊二酸的衍生物。 | |||
T2S0142 |
4-Hydroxylonchocarpin
异补骨脂色烯查耳酮,Isobavachromene |
Others | Others |
Isobavachromene is a natural product from Psoralea corylifolia | |||
T39887 |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid
(S)-3-(4-羟苯基)乳酸,(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid |
Others | Others |
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid ((S)-3-(4-Hydroxyphenyl)lactic acid) 是分离自间肠隐球菌培养基的代谢物,具有高的 DPPH 清除自由基活性和抗氧化活性。 | |||
T21367 |
Tetrahydrofolic acid
5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate |
Endogenous Metabolite | Metabolism |
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物,是生物体常见的一碳供体,参与生物体生长代谢。 | |||
T8260 |
4',5-Dihydroxyflavone
|
Lipoxygenase; Glucosidase | Metabolism |
4',5-Dihydroxyflavone 是大豆 LOX-1,Ki=102.6 μM。它也是一种酵母 α-葡萄糖苷酶抑制剂,IC50=66 μM。 | |||
T16535 |
Picrotoxinin
|
Chloride channel; GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Picrotoxinin 是一种氯离子通道阻断剂和 GABAA 的非竞争性拮抗剂,对 α1β2γ2L GABAA 的 IC50 为 1.15 μM。 Picrotoxinin 具有惊厥作用。 | |||
T3731 |
Hydrocinnamic acid
3-Phenylpropanoic acid,氢化肉桂酸,3-Phenylpropionic acid,3-Phenyl-n-propionic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Hydrocinnamic acid (3-Phenylpropanoic acid) 是一种根际化合物,具有生长调控活性。 | |||
TN1253 |
3-hydroxymorindone
|
Others | Others |
3-hydroxymorindone 是一种来自海巴戟 Morinda citrifolia 的天然产物。 3-hydroxymorindone 是一种色素。 | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05306 |
TRIM21 Protein, Human, Recombinant (His)
Ro/SSA,SSA,RO52,RNF81,tripartite motif con... |
Human | Baculovirus Insect Cells |
TRIM21 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 56.5 kDa and the accession number is P19474-1. | |||
TMPY-06327 |
Calreticulin Protein, Human, Recombinant
HEL-S-99n,calreticulin,cC1qR,CRT,RO,SSA |
Human | HEK293 Cells |
Calreticulin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.99 kDa and the accession number is P27797. | |||
TMPY-03258 |
Calreticulin Protein, Human, Recombinant (hFc)
RO,cC1qR,HEL-S-99n,CRT,calreticulin,SSA |
Human | HEK293 Cells |
Calreticulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73 kDa and the accession number is P27797. | |||
TMPY-03259 |
Calreticulin Protein, Human, Recombinant (His)
HEL-S-99n,cC1qR,SSA,CRT,RO,calreticulin |
Human | HEK293 Cells |
Calreticulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is P27797. | |||
TMPH-00864 |
RO60 Protein, Human, Recombinant (His)
|
Human | E. coli |
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes.; May play roles in cilia formation and/or maintenance. RO60 Protein, Human, Recombinant (His)... | |||
TMPY-03104 |
FGF-17 Protein, Human, Recombinant
fibroblast growth factor 17,HH20,FGF-13,FG... |
Human | E. coli |
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol... | |||
TMPY-02801 |
PHGDH Protein, Human, Recombinant (His)
phosphoglycerate dehydrogenase,HEL-S-113,3PGDH,NLS1... |
Human | E. coli |
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PH... | |||
TMPY-03958 |
TGF alpha Protein, Human, Recombinant
transforming growth factor α,转化生长因子,transforming g<... |
Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (... | |||
TMPY-02521 |
HIST3H2A Protein, Human, Recombinant
histone cluster 3, H2a,MGC3165 |
Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,... | |||
TMPY-02219 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein |
H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... | |||
TMPY-02869 |
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12 |
Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... | |||
TMPY-02062 |
SULT1A1 Protein, Human, Recombinant (His)
HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase family, cyt... |
Human | E. coli |
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa... | |||
TMPY-00105 |
Recombinant Protein G
|
E. coli | |
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... | |||
TMPY-00005 |
FGF-8a Protein, Human, Recombinant
fibroblast growth factor 8 (andro... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-02907 |
FGF-19 Protein, Human, Recombinant
fibroblast growth factor 19,FGF19 |
Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca... | |||
TMPY-06983 |
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interf... |
Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... | |||
TMPY-00006 |
GRO beta/CXCL2 Protein, Human, Recombinant
GROb,MIP-2a,CINC-2a,GRO β/CXCL2,MIP2,MGSA-... |
Human | E. coli |
GRO beta/CXCL2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.9 kDa and the accession number is A0A024RDD9. | |||
TMPY-02558 |
IL-4 Protein, Mouse, Recombinant
白介素,白细胞介素,BSF-1,Il-4,interleukin 4 |
Mouse | E. coli |
IL-4 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.4 kDa and the accession number is P07750. | |||
TMPY-03195 |
Serum Amyloid P Protein, Human, Recombinant (His)
amyloid P component, serum,HEL-S-92n,SAP,PTX2 |
Human | HEK293 Cells |
Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743. | |||
TMPY-03203 |
CD40 Protein, Rat, Recombinant (His)
CD40 molecule, TNF receptor superfamily member 5 |
Rat | HEK293 Cells |
CD40 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is A0A8I6A2T5. | |||
TMPK-00305 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. | |||
TMPK-00265 |
SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated
Nucleocapsid,NC,NP |
SARS-CoV-2 | E. coli |
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed in the cytoplasm of infected cells. SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 48.9 kDa and the accession number is P0DTC9. | |||
TMPK-00785 |
ANXA2 Protein, Mouse, Recombinant (His)
LIP2PAP-IV,Annexin II,LPC2DP36,LPC2D,CAL1H,Annexin A2,ANX2L4... |
Mouse | E. coli |
ANXA2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07356. | |||
TMPY-01802 |
c-Kit Protein, Mouse, Recombinant (His)
SCO5,SCO1,Bs,Gsfsco1,v-kit Hardy-Zuckerman 4 feline sarcoma ... |
Mouse | HEK293 Cells |
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P05532-1. | |||
TMPY-01936 |
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEG... |
Mouse | HEK293 Cells |
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1. | |||
TMPY-01807 |
NKp44/NCR2 Protein, Human, Recombinant (His)
RP1-149M18.2,LY95,dJ149M18.1,NK-p44,CD336,natural cytotoxici... |
Human | HEK293 Cells |
NKp44/NCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is O95944-1. | |||
TMPY-01864 |
CNTF Protein, Human, Recombinant (His)
ciliary neurotrophic factor,HCNTF |
Human | E. coli |
CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441. | |||
TMPY-01262 |
TROP-2 Protein, Human, Recombinant (His)
TROP2,M1S1,GA733-1,TROP-2,GA7331,tumor-ass... |
Human | HEK293 Cells |
TROP-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.4 kDa and the accession number is P09758. | |||
TMPY-01870 |
IL-9 Protein, Human, Recombinant (His)
P40,interleukin 9,HP40,白细胞介素,IL-9,白介素 |
Human | Baculovirus Insect Cells |
IL-9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P15248. | |||
TMPY-05176 |
AMH Protein, Human, Recombinant (His)
MIS,anti-Mullerian hormone,MIF |
Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi... | |||
TMPY-05102 |
CD122/IL2RB Protein, Rat, Recombinant (His)
interleukin 2 receptor, β,interleukin 2 receptor, beta |
Rat | HEK293 Cells |
CD122/IL2RB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P26896. | |||
TMPY-05054 |
Notch 4 Protein, Human, Recombinant (His)
INT3,notch 4 |
Human | Baculovirus Insect Cells |
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl... | |||
TMPY-02019 |
CD59 Protein, Human, Recombinant (His)
MIN2,MAC-IP,G344,EL32,FLJ92039,HRF-20,EJ30,HRF20,MSK21,MGC23... |
Human | HEK293 Cells |
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1. | |||
TMPY-04778 |
Prolactin Protein, Human, Recombinant (His)
prolactin |
Human | Baculovirus Insect Cells |
Prolactin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.3 kDa and the accession number is P01236. | |||
TMPY-04845 |
IL-3 Protein, Mouse, Recombinant
Il-3,白介素,PSF,HCGF,BPA,白细胞介素,MCGF,Csfmu,interleukin 3 |
Mouse | HEK293 Cells |
IL-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.7 kDa and the accession number is P01586. | |||
TMPY-00690 |
Carbonic Anhydrase 9 Protein, Human, Recombinant (His)
Carbonic Anhydrase IX,MN,CAIX |
Human | HEK293 Cells |
Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0. | |||
TMPY-02429 |
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His)
|
HCoV-HKU1 | HEK293 Cells |
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.8 kDa and the accession number is Q5MQD0. | |||
TMPY-04329 |
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin |
Human | Baculovirus Insect Cells |
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... | |||
TMPY-05584 |
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
CD25,p55,interleukin 2 receptor, alpha,TCGFR,IL-2RA,IDDM10,I... |
Human | HEK293 Cells |
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25 kDa and the accession number is P01589. | |||
TMPY-04529 |
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
epidermal growth factor receptor,PIG61,ERBB1,NISBD2... |
Human | Baculovirus Insect Cells |
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1. | |||
TMPY-03284 |
IL-T4 Protein, Human, Recombinant (His)
ILT-4,MIR-10,leukocyte immunoglobulin like receptor B2,LIR-2... |
Human | HEK293 Cells |
IL-T4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is AAH36827.1. | |||
TMPY-05202 |
Noggin/NOG Protein, Human, Recombinant
noggin,SYNS1,SYM1 |
Human | HEK293 Cells |
Noggin/NOG Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.1 kDa and the accession number is Q13253. | |||
TMPY-01686 |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
β-2 microglobulin,beta-2 microglobulin |
Human | HEK293 Cells |
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P61769. | |||
TMPY-01741 |
CD19 Protein, Mouse, Recombinant (His)
AW495831,CD19 molecule |
Mouse | HEK293 Cells |
CD19 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P25918. | |||
TMPY-00570 |
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placental,IAP,AL... |
Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. | |||
TMPY-05773 |
Human coronavirus (HCoV-HKU1) Nucleocapsid Protein (His)
|
HCoV-HKU1 | E. coli |
Human coronavirus (HCoV-HKU1) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 43.21 kDa and the accession number is Q19U25. | |||
TMPJ-00042 |
TSLP Protein, Human, Recombinant
TSLP,Thymic stromal lymphopoietin |
Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral... | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-03357 |
FGFR2 Protein, Mouse, Recombinant (hFc)
KGFR,AU043015,KGFRTr,Bek,Fgfr7,svs,fibroblast g... |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is AAA39377.1. | |||
TMPY-02204 |
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding protein |
Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... | |||
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