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OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Synonyms: Tumor necrosis factor ligand 2B, TNFSF4, OX-40L
货号 TMPJ-01441 一键复制产品信息
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Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

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货号 TMPJ-01441

别名 Tumor necrosis factor ligand 2B, TNFSF4, OX-40L

Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.

OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
其他形式的 “OX40L/TNFSF4 Trimer Protein, Cynomolgus/Rhesus macaque, Recombinant (His)”:
规格价格库存数量
5 μg
¥ 343
2-4周
10 μg
¥ 550
2-4周
20 μg
¥ 878
2-4周
50 μg
¥ 1,670
2-4周
100 μg
¥ 3,120
2-4周
200 μg
¥ 5,890
2-4周
500 μg
¥ 13,700
2-4周
1 mg
¥ 20,500
2-4周
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产品介绍


生物活性
产品描述
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
生物活性
Immobilized Cynomolgus/Rhesus macaque OX40 Ligand, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human OX40, hFc Tag with the EC50 of 18.7 ng/ml determined by ELISA.
研究背景
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells.
种属
Cynomolgus/Rhesus macaque
表达系统
HEK293 Cells
标签
N-His
蛋白编号A0A2K5TTN0(Cynomolgus) / A0A1D5QQH7(Rhesus macaque)
蛋白构建
Gln81-Leu213 (Cynomolgus) / Gln51-Leu183 (Rhesus macaque)
蛋白纯度
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
Tumor necrosis factor ligand 2B, TNFSF4, OX-40L
内毒素<1 EU/µg as determined by LAL test.
化学信息
分子量17.01 kDa (predicted); 25-38 kDa (due to glycosylation); 60-70 kDa (SEC-MALS)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

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