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GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)

Synonyms: GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144
货号 TMPK-01052 一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.1 kDa and the accession number is Q6SJE0-1.

GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPK-01052

别名 GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.1 kDa and the accession number is Q6SJE0-1.

GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)
其他形式的 “GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)”:
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated
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规格价格库存数量
5 μg
¥ 358
现货
10 μg
¥ 573
现货
20 μg
¥ 938
现货
50 μg
¥ 1,830
3日内发货
100 μg
¥ 3,100
现货
200 μg
¥ 5,620
5日内发货
500 μg
¥ 12,400
5日内发货
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纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍

生物活性
产品描述
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 40.1 kDa and the accession number is Q6SJE0-1.
生物活性
1. Immobilized Mouse GFRAL, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Mouse GDF15, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). 2. Mouse GFRAL, His Tag immobilized on CM5 Chip can bind Mouse GDF15, His Tag with an affinity constant of 0.34 nM as determined in SPR assay.
研究背景
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
种属
Mouse
表达系统
HEK293 Cells
标签N-His-Avi
蛋白编号Q6SJE0-1
蛋白构建Gln20-Glu350
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名GRAL, GFRAL/GFR α-like Protein, GFRAL, GFR α-like, GFR alpha-like, C6orf144
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量40.1 kDa (predicted). Due to glycosylation, the protein migrates to 48-60 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

GFR a-like
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