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ASPH Protein, Human, Recombinant (His)

ASPH Protein, Human, Recombinant (His)

产品编号 TMPK-00945
别名: Aspartate beta-hydroxylase, ASP beta-hydroxylase, Asph, Bah, Aspartate β-hydroxylase, ASP β-hydroxylase

Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q12797-1.

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ASPH Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 2,660 5日内发货
500 μg ¥ 10,600 5日内发货
1 mg ¥ 17,800 5日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: ASPH Protein, Human, Recombinant (His) (TMPK-00945)
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参考文献
产品描述 Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q12797-1.
种属 Human
表达系统 E. coli
标签 N-His
蛋白编号 Q12797-1
别名 Aspartate beta-hydroxylase, ASP beta-hydroxylase, Asph, Bah, Aspartate β-hydroxylase, ASP β-hydroxylase
蛋白构建 Ile341-Ile758
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 49.2 kDa (predicted) same as Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 7.4).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.

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Keywords

ASPH Protein, Human, Recombinant (His) Aspartate beta-hydroxylase ASP beta-hydroxylase Asph ASP b-hydroxylase Bah Aspartate β-hydroxylase Aspartate b-hydroxylase ASP β-hydroxylase recombinant recombinant-proteins proteins protein

 

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