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ASPH Protein, Human, Recombinant (His)

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货号 TMPK-00945

别名 Bah, Asph, Aspartate β-hydroxylase, Aspartate beta-hydroxylase, ASP β-hydroxylase, ASP beta-hydroxylase

Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q12797-1.

ASPH Protein, Human, Recombinant (His)
其他形式的 “ASPH Protein, Human, Recombinant (His)”:

ASPH Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 还可以
货号 TMPK-00945 别名 Bah, Asph, Aspartate β-hydroxylase, Aspartate beta-hydroxylase, ASP β-hydroxylase, ASP beta-hydroxylase

Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q12797-1.

规格价格库存数量
5 μg
¥ 313
6-8日内发货
10 μg
¥ 498
6-8日内发货
20 μg
¥ 793
5日内发货
50 μg
¥ 1,580
5日内发货
100 μg
¥ 2,660
5日内发货
200 μg
¥ 4,790
5日内发货
500 μg
¥ 10,600
5日内发货
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产品介绍


生物活性
产品描述
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.2 kDa and the accession number is Q12797-1.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.
种属
Human
表达系统
E. coli
标签N-His
蛋白编号Q12797-1
蛋白构建Ile341-Ile758
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 7.4).
别名Bah, Asph, Aspartate β-hydroxylase, Aspartate beta-hydroxylase, ASP β-hydroxylase, ASP beta-hydroxylase
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量49.2 kDa (predicted) same as Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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