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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

产品编号 TMPJ-00607
别名: Receptor activator of nuclear factor κ-B ligand, Osteoprotegerin ligand, OPGL, TNF-related activation-induced cytokine, CD254, Receptor activator of nuclear factor kappa-B ligand, ODF, RANKL, TRANCE, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Tnfsf11

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.

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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 现货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) (TMPJ-00607)
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生物活性
技术参数
产品性质
生物活性 Loaded Recombinant Human OPG-Fc on Pro A Biosensor, can bind Mouse RANKL-His with an affinity constant of 1.02 pM as determined in BLI assay. (Regularly tested)

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产品描述 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
种属 Mouse
表达系统 HEK293 Cells
标签 N-6xHis
蛋白编号 BAA97257.1
别名 Receptor activator of nuclear factor κ-B ligand, Osteoprotegerin ligand, OPGL, TNF-related activation-induced cytokine, CD254, Receptor activator of nuclear factor kappa-B ligand, ODF, RANKL, TRANCE, Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, Tnfsf11
氨基酸序列 Arg43-Asp287
蛋白构建 Arg43-Asp287
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. Greater than 90% as determined by SEC-HPLC.

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分子量 30-35 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Hepes-NaOH, 50 mM NaCl, 6% Trehalose, 4% Mannitol, 0.05% Tween 80, pH 8.0.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

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Keywords

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) Receptor activator of nuclear factor k-B ligand CD-254 Receptor activator of nuclear factor κ-B ligand Osteoprotegerin ligand OPGL TNF-related activation-induced cytokine CD254 Receptor activator of nuclear factor kappa-B ligand ODF RANKL TRANCE Tumor necrosis factor ligand superfamily member 11 CD 254 Osteoclast differentiation factor Tnfsf11 recombinant recombinant-proteins proteins protein

 

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