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Anti-Marapsin Antibody (8D452)

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产品编号 TMAY-02242
别名 UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2

Anti-Marapsin Antibody (8D452) 是一种 Mouse 抗体,靶向 Marapsin。Anti-Marapsin Antibody (8D452) 可用于 ELISA。

Anti-Marapsin Antibody (8D452)

Anti-Marapsin Antibody (8D452)

Rating icon 还可以
产品编号 TMAY-02242 别名 UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2

Anti-Marapsin Antibody (8D452) 是一种 Mouse 抗体,靶向 Marapsin。Anti-Marapsin Antibody (8D452) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-Marapsin Antibody (8D452) is a Mouse antibody targeting Marapsin. Anti-Marapsin Antibody (8D452) can be used in ELISA.
别名UNQ1884/PRO4327, protease, serine 27, MPN, CAPH2
Ig Type
Monoclonal Mouse IgG1
克隆号
8D452
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Pancreasin / Marapsin / PRSS27 (rh Pancreasin / Marapsin / PRSS27; TMPY-02117; Q9BQR3; Met1-Lys290). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most strongly up-regulated protease in psoriatic lesions, where expression was localized to the upper region of the hyperplastic epidermis. Similarly, in the hyperproliferative epithelium of regenerating murine skin wounds, marapsin localized to the suprabasal layers, where keratinocytes undergo squamous differentiation. Marapsin's restricted expression, localization, and cytokine-inducible expression suggest a role in the terminal differentiation of keratinocytes in hyperproliferating squamous epithelia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Pancreasin / Marapsin / PRSS27 protein (TMPY-02117)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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