Tetrachlorohydroquinone

Name: Tetrachlorohydroquinone
Brand: TargetMol
SKU: T36507
Rating: 4.5 (1 reviews)

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产品编号 T36507Cas号 87-87-6

Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.

Tetrachlorohydroquinone

还可以

产品编号 T36507Cas号 87-87-6

规格	价格	库存
1 g	待估	35日内发货
5 g	待估	35日内发货
10 g	待估	35日内发货

大包装 & 定制

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产品介绍

生物活性

产品描述	Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.
体内活性	In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.

化学信息

分子量	247.89
分子式	C₆H₂Cl₄O₂
CAS No.	87-87-6

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMF: 30 mg/mL (121.02 mM), Sonication is recommended.

Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL (2.02 mM), Sonication is recommended.

DMSO: 30 mg/mL (121.02 mM), Sonication is recommended.

Ethanol: 30 mg/mL (121.02 mM), Sonication is recommended.

溶液配制表

DMF/DMSO/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.8068 mL	4.0340 mL	8.0681 mL	40.3405 mL
10 mM	0.4034 mL	2.0170 mL	4.0340 mL	20.1702 mL
20 mM	0.2017 mL	1.0085 mL	2.0170 mL	10.0851 mL
50 mM	0.0807 mL	0.4034 mL	0.8068 mL	4.0340 mL
100 mM	0.0403 mL	0.2017 mL	0.4034 mL	2.0170 mL