SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 2,260 | 现货 | ||
100 μg | ¥ 3,880 | 5日内发货 | ||
200 μg | ¥ 6,630 | 5日内发货 | ||
500 μg | ¥ 13,410 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | Tag Free |
蛋白编号 | Q9UBE0 |
别名 | SUA1, SUMO1 activating enzyme subunit 1, HSPC140, UBLE1A, AOS1 |
蛋白构建 | The Human SAE1 (Q9UBE0) (Met1-Lys346) was expressed and purified. |
蛋白纯度 |
> 95 % as determined by SDS-PAGE
|
分子量 | 38.6 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM Nacl, pH 7.4, 10% glycerol. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. SAE1 also regulates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. |
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SAE1 Protein, Human, Recombinant SUA1 SUMO1 activating enzyme subunit 1 SUA-1 HSPC140 UBLE1A AOS1 HSPC-140 HSPC 140 AOS-1 AOS 1 SUA 1 recombinant recombinant-proteins proteins protein