Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 76.6 kDa and the accession number is A0A2K5USI5.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 5,180 | 5日内发货 | ||
500 μg | ¥ 20,700 | 5日内发货 | ||
1 mg | ¥ 34,600 | 5日内发货 |
产品描述 | Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 76.6 kDa and the accession number is A0A2K5USI5. |
种属 | Cynomolgus |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | A0A2K5USI5 |
别名 | Protein-arginine deiminase type-4, HL60 PAD, PAD, PDI5, PADI5, PAD4, HL-60, HL-60 PAD |
蛋白构建 | Met1-Pro663 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | 76.6 kDa (predicted) same as Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM Nacl, 10% Glycerol, 0.5 mM TCEP, 1 mM EDTA (pH 8.0). |
存储 |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. |
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PADI4 Protein, Cynomolgus, Recombinant (His) Protein-arginine deiminase type-4 HL60 PAD PAD PAD 4 PDI 5 HL 60 PDI-5 PAD-4 HL60 PDI5 PADI 5 PADI-5 PADI5 PAD4 HL-60 HL-60 PAD recombinant recombinant-proteins proteins protein