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Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
还可以产品编号 TMAY-01591
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) 是一种 Mouse 抗体，靶向 Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G。Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) 可用于 WB,ELISA。
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
还可以产品编号 TMAY-01591
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) 是一种 Mouse 抗体，靶向 Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G。Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 785 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G. Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5J298 |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: 1:500-1:1000; ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RSV Glycoprotein G/RSV-G (HRSV-G; Asn66-Arg297P27022-1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. HRSV G protein is a type II glycoprotein of 289-299 amino acids (depending on the virus strain) with a signal/anchor hydrophobic domain and is extensively modified by the addition of both N-and O-linked oligosaccharides to achieve the mature form of 8-9 kDa. The C-terminal ectodomain of the G protein has a central region and four cysteines which are conserved in all HRSV isolates and have been proposed as the putative receptor binding site. The G protein mediates attachment of the virus to the host cell membrane by interacting with heparan sulfate, initiating the infection. As similar to mucins in amino acid compositions, the RSV G protein can interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, and thus modulates the immune response and facilitate infection. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors. Unlike the other paramyxovirus attachment proteins, HRSV-G lacks both neuraminidase and hemagglutinating activities. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human RSV Glycoprotein G / RSV-G |
| 抗原种属 | RSV |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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