Name: LEAP-2
Brand: TargetMol
SKU: T81944
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,238

5日内发货

生物活性

产品描述	LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide and an endogenous competitive antagonist of growth hormone-releasing peptide, as well as a reverse agonist of constitutive GHS-R1a activity, used for research on obesity and other metabolic diseases.
体内活性	LEAP-2 （0.3， 1， 3 nmol/大鼠，ICV）预处理，在 12 h 自由进食状态下以剂量依赖性方式抑制大鼠生长素释放肽诱导的食物摄入。[2]
别名	Human liver expressed antimicrobial peptide-2

化学信息

CAS No.	1683582-94-6
Sequence	Met-Thr-Pro-Phe-Trp-Arg-Gly-Val-Ser-Leu-Arg-Pro-Ile-Gly-Ala-Ser-Cys-Arg-Asp-Asp-Ser-Glu-Cys-Ile-Thr-Arg-Leu-Cys-Arg-Lys-Arg-Arg-Cys-Ser-Leu-Ser-Val-Ala-Gln-Glu (Disulfide bridge:Cys17-Cys28;Cys23-Cys33)
Sequence Short	MTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE (Disulfide bridge:Cys17-Cys28;Cys23-Cys33)

储存&溶解度

存储	keep away from moisture,store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: 80 mg/mL, Sonication is recommended.

LEAP-2