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别名 Human liver expressed antimicrobial peptide-2
LEAP-2 (Human liver expressed antimicrobial peptide-2) 是一种抗菌肽,是生长素释放肽的内源性竞争性拮抗剂,也是组成型 GHS-R1a 活性的反向激动剂,可用于研究肥胖和其他代谢疾病。
LEAP-2 (Human liver expressed antimicrobial peptide-2) 是一种抗菌肽,是生长素释放肽的内源性竞争性拮抗剂,也是组成型 GHS-R1a 活性的反向激动剂,可用于研究肥胖和其他代谢疾病。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,238 | 5日内发货 |
LEAP-2 相关产品
| 产品描述 | LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide and an endogenous competitive antagonist of growth hormone-releasing peptide, as well as a reverse agonist of constitutive GHS-R1a activity, used for research on obesity and other metabolic diseases. |
| 体内活性 | LEAP-2 (0.3, 1, 3 nmol/大鼠,ICV)预处理,在 12 h 自由进食状态下以剂量依赖性方式抑制大鼠生长素释放肽诱导的食物摄入。[2] |
| 别名 | Human liver expressed antimicrobial peptide-2 |
| CAS No. | 1683582-94-6 |
| Sequence | Met-Thr-Pro-Phe-Trp-Arg-Gly-Val-Ser-Leu-Arg-Pro-Ile-Gly-Ala-Ser-Cys-Arg-Asp-Asp-Ser-Glu-Cys-Ile-Thr-Arg-Leu-Cys-Arg-Lys-Arg-Arg-Cys-Ser-Leu-Ser-Val-Ala-Gln-Glu (Disulfide bridge:Cys17-Cys28;Cys23-Cys33) |
| Sequence Short | MTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE (Disulfide bridge:Cys17-Cys28;Cys23-Cys33) |
| 存储 | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度信息 | DMSO: 80 mg/mL, Sonication is recommended. |
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