规格

价格

库存

数量

2 mg

¥ 533

5日内发货

5 mg

¥ 945

5日内发货

100 mg

¥ 8,730

6-8周

生物活性

产品描述	SKF-82958 hydrobromide is a D1/D5 receptor full agonist.
体外活性	Neuropeptide and immediate early gene expression in striatonigral neurons of the normotensive striatum is induced by mixed D1 receptor SKF-82958, which induces behavioral activity and preprodynorphin (PPD) and substance P (SP) gene expression in medium spiny neurons in the dorsal, and especially, in the ventral striatum.
体内活性	Quantitative in situ hybridization was used to examine the contribution of muscarinic receptors to the transsynaptic regulation of striatal gene expression induced by D1receptor activation. The acute injection of the full D1 agonist, SKF-82958, would induce PPD, SP, and PPE mRNA expression in the intact rat striatum.
别名	Chloro-APB hydrobromide, (±)-SKF 82958 hydrobromide

化学信息

分子量	410.73
分子式	C₁₉H₂₁BrClNO₂
CAS No.	74115-01-8
Smiles	Br.Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 102.5 mg/mL (249.56 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (8.03 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO