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HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00453

别名 p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.

HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

HER3/ERBB3 Protein, Human, Recombinant (His & Avi)

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Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00453 别名 p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.

规格价格库存数量
5 μg
¥ 223
6-8日内发货
10 μg
¥ 345
6-8日内发货
20 μg
¥ 552
5日内发货
50 μg
¥ 1,060
5日内发货
100 μg
¥ 1,770
5日内发货
200 μg
¥ 3,190
5日内发货
500 μg
¥ 7,110
5日内发货
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产品介绍


生物活性
产品描述
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1.
生物活性
Immobilized Human Her3, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 48.6ng/ml determined by ELISA.
研究背景
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号P21860-1
蛋白构建Ser20-Thr643
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ErbB3
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量71.6 kDa (predicted). Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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