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MMP-14 Protein, Human, Recombinant (His & SUMO)

Synonyms: MMP-X1, MMP-14, MMP14, Membrane-type-1 matrix metalloproteinase (MT1-MMP;MT1MMP), Membrane-type matrix metalloproteinase 1 (MT-MMP 1;MTMMP1), Matrix metalloproteinase-14
货号 TMPH-00010 一键复制产品信息
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Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.

MMP-14 Protein, Human, Recombinant (His & SUMO)

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货号 TMPH-00010

别名 MMP-X1, MMP-14, MMP14, Membrane-type-1 matrix metalloproteinase (MT1-MMP;MT1MMP), Membrane-type matrix metalloproteinase 1 (MT-MMP 1;MTMMP1), Matrix metalloproteinase-14

Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.

MMP-14 Protein, Human, Recombinant (His & SUMO)
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规格价格库存数量
5 μg
¥ 489
3日内发货
10 μg
¥ 797
现货
20 μg
¥ 1,320
现货
50 μg
¥ 1,970
3日内发货
100 μg
¥ 2,680
现货
200 μg
¥ 4,160
20日内发货
500 μg
¥ 7,490
20日内发货
1 mg
¥ 11,700
20日内发货
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纯度: > 90 % as determined by SDS-PAGE
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.
种属
Human
表达系统
E. coli
标签
N-6xHis-SUMO
蛋白编号P50281
氨基酸序列
YAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
蛋白构建
112-582 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
MMP-14 Protein, Human, Recombinant (His & SUMO)
缓冲液
Tris-based buffer, 50% glycerol
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
MMP-X1, MMP-14, MMP14, Membrane-type-1 matrix metalloproteinase (MT1-MMP;MT1MMP), Membrane-type matrix metalloproteinase 1 (MT-MMP 1;MTMMP1), Matrix metalloproteinase-14
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量69.9 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

MT-MMP1MT-MMP 1MT1-MMPMT 1-MMPMMPX1MMP 14
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