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顶部相关产品产品介绍化学信息储存和溶解信息计算器

17-phenyl trinor Prostaglandin F2α methyl amide

Synonyms: 17-phenyl trinor Prostaglandin F2α methyl amide
货号 T37944Cas号 155206-01-2 一键复制产品信息
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17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

17-phenyl trinor Prostaglandin F2α methyl amide

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货号 T37944Cas号 155206-01-2

别名 17-phenyl trinor Prostaglandin F2α methyl amide

17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

17-phenyl trinor Prostaglandin F2α methyl amide
规格价格库存数量
1 mg
¥ 1,430
35日内发货
5 mg
¥ 6,300
35日内发货
10 mg
¥ 8,850
35日内发货
50 mg
¥ 22,300
35日内发货
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产品介绍

生物活性
产品描述
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The ethyl amide of 17-phenyl trinor PGF2α bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF2α methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.
别名
17-phenyl trinor Prostaglandin F2α methyl amide
化学信息
分子量401.547
分子式C24H35NO4
CAS No.155206-01-2
SmilesCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
DMF: 25 mg/mL (62.26 mM), Sonication is recommended.
PBS (pH 7.2): 300 μg/mL, Sonication is recommended.
Ethanol: 50 mg/mL (124.52 mM), Sonication is recommended.
Acetonitrile: 3 mg/mL (7.47 mM), Sonication is recommended.
DMSO: 25 mg/mL (62.26 mM), Sonication is recommended.
溶液配制表
Acetonitrile/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.4904 mL12.4518 mL24.9037 mL124.5184 mL
5 mM0.4981 mL2.4904 mL4.9807 mL24.9037 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
10 mM0.2490 mL1.2452 mL2.4904 mL12.4518 mL
20 mM0.1245 mL0.6226 mL1.2452 mL6.2259 mL
50 mM0.0498 mL0.2490 mL0.4981 mL2.4904 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

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