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FGF-8b Protein, Human, Recombinant

FGF-8b Protein, Human, Recombinant

产品编号 TMPY-06986
别名: NEWENTRY, fibroblast growth factor 8 (androgen-induced), FGF-8, KAL6, AIGF, HH6, HBGF-8

In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.

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FGF-8b Protein, Human, Recombinant
规格 价格/CNY 货期 数量
50 μg ¥ 2,940 现货
100 μg ¥ 5,010 5日内发货
200 μg ¥ 8,510 5日内发货
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产品目录号及名称: FGF-8b Protein, Human, Recombinant (TMPY-06986)
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生物活性
技术参数
产品性质
生物活性 Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.4-1.6 μg/mL.
产品描述 In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
种属 Human
表达系统 E. coli
标签 Tag Free
蛋白编号 P55075-3
别名 NEWENTRY, fibroblast growth factor 8 (androgen-induced), FGF-8, KAL6, AIGF, HH6, HBGF-8
蛋白构建 The Human FGF8b (P55075-3) (Gln23-Arg215) was expressed with an initial Met.
蛋白纯度 > 95 % as determined by SDS-PAGE.
分子量 The recombinant human FGF8b consists 194 amino acids and predicts a molecular mass of 22.5 kDa.
内毒素 Please contact us for more information.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. . Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.

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Keywords

FGF-8b Protein, Human, Recombinant fibroblast growth factor 8 HH-6 NEWENTRY fibroblast growth factor 8 (androgen-induced) HBGF 8 FGF-8 KAL6 FGF 8 AIGF KAL 6 HH6 androgen-induced HBGF-8 KAL-6 HBGF8 FGF8 HH 6 recombinant recombinant-proteins proteins protein

 

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