Name: Cholesterol oxidase
Brand: TargetMol
SKU: T76128
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 KU

¥ 4,000

5日内发货

生物活性

产品描述	Cholesterol oxidase is a flavoenzyme that catalyzes the oxidation and isomerization of cholesterol to cholest-4-en-3-one. ChOx, an important virulence factor for Mycobacterium tuberculosis (Mtb), competitively inhibits TLR2 thereby inducing enhanced reactive oxygen species production by macrophages.
靶点活性	MCF-7 cells:75.3%(cell viability inhibition at 23 UmL−1), HCT116 cells:64.6%(cell viability inhibition at 23 UmL−1), HeLa cells:62.9%(cell viability inhibition at 23 UmL−1), HepG2 cells:69.4%(cell viability inhibition at 23 UmL−1)
体外活性	通过MTT实验法，Cholesterol oxidase（23 U/mL）对HepG-2、HCT-116等癌细胞的抑制率为62.9%-78.7%，对正常WI-38细胞的抑制率为57.2%。此外，Cholesterol oxidase还可用于检测血清、食物样本中的胆固醇（在37°C孵育10分钟）以及细胞/组织中的胆固醇（使用AmplexRed荧光法）[1,2]。
别名	胆固醇氧化酶, ChOx

化学信息

储存&溶解度

存储	store at low temperature,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	H2O: 20 mg/mL, Sonication is recommended.