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Oxyphenonium bromide

Name: Oxyphenonium bromide
Brand: TargetMol
SKU: T33846
Price: 128 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 奥芬溴铵, Spasmophen, Oxyphenon, Oxyfenon, Oxifenon, Atrenyl

货号 T33846Cas号 50-10-2 一键复制产品信息纯度: 98.96%

很棒

Oxyphenonium bromide (Oxyfenon) 具有抗胆碱能活性，可用于治疗胃和十二指肠溃疡以及缓解内脏痉挛的研究。

Oxyphenonium bromide

一键复制产品信息

很棒

纯度: 98.96%

货号 T33846Cas号 50-10-2

别名 奥芬溴铵, Spasmophen, Oxyphenon, Oxyfenon, Oxifenon, Atrenyl

Oxyphenonium bromide (Oxyfenon) 具有抗胆碱能活性，可用于治疗胃和十二指肠溃疡以及缓解内脏痉挛的研究。

规格	价格	库存
2 mg	¥ 128	现货
5 mg	¥ 189	现货
10 mg	¥ 289	现货
25 mg	¥ 482	现货
50 mg	¥ 688	现货
100 mg	¥ 987	现货
1 mL x 10 mM (in DMSO)	¥ 253	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 98.96%

颜色: 白色

性状: Solid

资源下载: COA LCMS HNMR产品操作手册

产品介绍

Oxyphenonium bromide AI Summary

Oxyphenonium bromide exhibits diverse bioactivities across various biological assays. It demonstrates significant potency in multiple quantitative high-throughput screening (qHTS) assays, including 730.8 nM for lipid storage modulators in Drosophila S3 cells, 1122.0 nM for inhibitors of cell surface uPA generation, 281.8 nM for TGF-b inhibitors, and 1258.9 nM for DNA re-replication in SW480 colon adenocarcinoma cells. Additionally, it shows varied potencies in primary qHTS assays for delayed death inhibitors of the malarial parasite plastid (11689.1 nM and 13115.4 nM), Nrf2 inhibitors (ranging from 7307.8 nM to 18356.4 nM), HP1-beta chromodomain interactions inhibitors (112201.8 nM), and inhibitors of Pin1 (44668.4 nM). Moreover, Oxyphenonium bromide displays antiviral activities, including inhibiting SARS-CoV-2 induced cytotoxicity in Caco-2 cells (1.46% inhibition at 10 µM) and VERO-6 cells (0.37% inhibition at 10 µM). It also acts as a SARS-CoV-2 3CL-Pro protease inhibitor with a 9.003% inhibition at 20 µM, as determined by a FRET assay. Furthermore, it exhibits an AC50 of 7.943 µM for blocking Ebola Virus entry. In terms of antibacterial and antifungal activities, Oxyphenonium bromide inhibits various strains including Escherichia coli (3.27% inhibition), Klebsiella pneumoniae (20.0% inhibition), Pseudomonas aeruginosa (14.05% inhibition), Acinetobacter baumannii (27.96% inhibition), and Staphylococcus aureus MRSA (12.65% inhibition). It also demonstrates antifungal activity against Candida albicans with 2.42% inhibition, while showing negative inhibition against Cryptococcus neoformans (-6.44%), indicating lack of activity or possible stimulation. Overall, Oxyphenonium bromide's bioactivities encompass inhibiting lipid storage, various enzymes, viral entry, and exhibiting antibacterial and antifungal effects, highlighting its broad-spectrum potential..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms.
别名	奥芬溴铵, Spasmophen, Oxyphenon, Oxyfenon, Oxifenon, Atrenyl

化学信息

分子量	428.404
分子式	C₂₁H₃₄BrNO₃
CAS No.	50-10-2
Smiles	[Br-].CC[N+](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
密度	1.2584 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 27.5 mg/mL (64.19 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3342 mL	11.6712 mL	23.3425 mL	116.7123 mL
5 mM	0.4668 mL	2.3342 mL	4.6685 mL	23.3425 mL
10 mM	0.2334 mL	1.1671 mL	2.3342 mL	11.6712 mL
20 mM	0.1167 mL	0.5836 mL	1.1671 mL	5.8356 mL
50 mM	0.0467 mL	0.2334 mL	0.4668 mL	2.3342 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。