Name: LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated
Brand: TargetMol
SKU: TMPJ-00552
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 815

6-8日内发货

10 μg

¥ 1,350

6-8日内发货

20 μg

¥ 2,260

5日内发货

50 μg

¥ 3,980

5日内发货

100 μg

¥ 6,130

5日内发货

生物活性

产品描述	Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo.
种属	Human
表达系统	HEK293 Cells
标签	C-Avi-6xHis
蛋白编号	AAH36827.1
氨基酸序列	Gln22-His458
蛋白构建	Gln22-His458
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Monocyte/Macrophage Immunoglobulin-Like Receptor 10, MIR-10, LIR-2, Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, Leukocyte Immunoglobulin-Like Receptor 2, L, Immunoglobulin-Like Transcript 4, ILT-4, CD85d, CD85 Antigen-Like Family Member D
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	60-80 KDa (reducing condition)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated

LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated

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