Cefprozil

Name: Cefprozil
Brand: TargetMol
SKU: T1118L
Price: 1780 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 98.1%

货号 T1118LCas号 92665-29-7

别名 Cefzil, Cefprozilum, Cefprozilo, Cefprozil anhydrous, Brisoral

Cefprozil (Cefzil) 是一种新型头孢菌素类抗生素，具有抗病毒活性，可用于研究免疫系统疾病。

Cefprozil

一键复制产品信息

很棒

纯度: 98.1%

货号 T1118L 别名 Cefzil, Cefprozilum, Cefprozilo, Cefprozil anhydrous, BrisoralCas号 92665-29-7

Cefprozil (Cefzil) 是一种新型头孢菌素类抗生素，具有抗病毒活性，可用于研究免疫系统疾病。

规格	价格	库存
1 mg	¥ 1,780	现货
5 mg	¥ 4,480	现货
10 mg	¥ 6,380	现货
25 mg	¥ 9,620	现货
50 mg	¥ 12,900	现货

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产品介绍

Cefprozil AI Summary

Cefprozil exhibits antimicrobial activity against several resistant strains of Haemophilus influenzae, including rifampin-resistant, beta lactamase-nonproducing ampicillin-resistant strains with various mutations in penicillin-binding protein 3, with a minimum inhibitory concentration (MIC) of 4.0 µg/mL. In humans, after intravenous administration, the compound has a pharmacokinetic profile characterized by a volume of distribution at steady state (Vdss) of 0.21 L/kg, a fraction unbound (Fu) of 0.59, a mean residence time (MRT) of 1.2 hours, a half-life (T1/2) of 1.2 hours, and a clearance (CL) of 2.9 mL/min/kg. Additionally, it significantly affects liver function, causing increases in several liver enzymes such as lactate dehydrogenase (LDH), gamma-glutamyl transferase (GGT), and serum transaminases (SGOT, SGPT), and demonstrating moderate hepatotoxicity. The compound shows notable effects on drug-induced liver injury with a HepSE score of 1.0 for jaundice but does not significantly impact other hepatic side effects. Clinically, its hepatotoxic effects include acute, cytolytic, and cholestatic liver toxicity with a DILI severity class of 4.0. In vitro assays have also revealed that Cefprozil primarily exhibits binding affinity towards numerous receptors (e.g., ADRB2, CHRNA4, DRD2) and enzymes, although it generally lacks significant inhibitory activity, with most AC50 values exceeding 30000 nM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Cefprozil (Cefzil) is a novel cephalosporin antibiotic with antiviral activity for the study of immune system disorders.
别名	Cefzil, Cefprozilum, Cefprozilo, Cefprozil anhydrous, Brisoral

化学信息

分子量	389.43
分子式	C₁₈H₁₉N₃O₅S
CAS No.	92665-29-7
Smiles	[H][C@](N)(C(=O)N[C@]1([H])C(=O)N2C(C(O)=O)=C(CS[C@]12[H])C=CC)c1ccc(O)cc1
密度	1.53 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储	store at low temperature,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.