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别名 cytotoxic and regulatory T cell molecule, CD355
CRTAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is O95727.

CRTAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is O95727.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 428 | 6-8日内发货 | |
| 10 μg | ¥ 683 | 6-8日内发货 | |
| 20 μg | ¥ 1,130 | 5日内发货 | |
| 50 μg | ¥ 2,270 | 5日内发货 | |
| 100 μg | ¥ 4,430 | 5日内发货 |
| 产品描述 | CRTAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is O95727. |
| 生物活性 | Immobilized Human CRTAM, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CRTAM Antibody, hFc Tag with the EC50 of 57.3 ng/ml determined by ELISA. |
| 研究背景 | Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | O95727-1 |
| 蛋白构建 | Ser18-Gly287 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | cytotoxic and regulatory T cell molecule, CD355 |
| 内毒素 | Less than 1EU per μg by the LAL method. |
| 分子量 | 31.1 kDa (Predicted); 55-70 kDa (Due to glycosylation) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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