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Anti-M-CSF/CSF1 Antibody (1B24) 是一种 Mouse 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (1B24) 可用于 ELISA。
Anti-M-CSF/CSF1 Antibody (1B24) 是一种 Mouse 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (1B24) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,689 | 5日内发货 |
产品描述 | Anti-M-CSF/CSF1 Antibody (1B24) is a Mouse antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (1B24) can be used in ELISA. |
别名 | 集落刺激因子, M-CSF, MCSF, CSF-1, colony stimulating factor 1 (macrophage) |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1B24 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human M-CSF/CSF-1 (rh M-CSF/CSF-1; P09603-1Met1-Asn190). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression. |
偶联 | Unconjugated |
免疫原 | Recombinant Human M-CSF/CSF-1 Protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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