购物车
- 全部删除
您的购物车当前为空
Anti-PDGFRA Antibody (1K967)
还可以产品编号 TMAY-00967
别名 platelet-derived growth factor receptor, α polypeptide, platelet-derived growth factor receptor, alpha polypeptide
Anti-PDGFRA Antibody (1K967) 是一种 Mouse 抗体，靶向 PDGFRA。Anti-PDGFRA Antibody (1K967) 可用于 ELISA,FCM。
Anti-PDGFRA Antibody (1K967)
Anti-PDGFRA Antibody (1K967)
还可以产品编号 TMAY-00967 别名 platelet-derived growth factor receptor, α polypeptide, platelet-derived growth factor receptor, alpha polypeptide
Anti-PDGFRA Antibody (1K967) 是一种 Mouse 抗体，靶向 PDGFRA。Anti-PDGFRA Antibody (1K967) 可用于 ELISA,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,694 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PDGFRA Antibody (1K967) is a Mouse antibody targeting PDGFRA. Anti-PDGFRA Antibody (1K967) can be used in ELISA,FCM. |
| 别名 | platelet-derived growth factor receptor, α polypeptide, platelet-derived growth factor receptor, alpha polypeptide |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1K967 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human PDGFRα (CD140a) expression on MG63 cells. Cells were stained with purified anti-Human PDGFRα (CD140a), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PDGFRA / CD140a (rh PDGFRA / CD140a; TMPY-01139; NP_006197.1; Met1-Glu524). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfamily of receptor tyrosine kinase (RTKs) with the similar structure characteristics of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGFRA is expressed in oligodendrocyte progenitor cells and mesothelial cell, and binds all three ligand isoforms PDGF-AA, PDGF-BB and PDGF-AB with high affinity, whereas PDGFRB dose not bind PDGF-AA. PDGFRA plays an essential role in regulating proliferation, chemotaxis and migration of mesangial cells. Recent studies have indicated that PDGFRA acts as a critical mediator of signaling in testis organogenesis and Leydig cell differentiation, and in addition, particularly important for kidney development. Additionally, PDGFRA is involved in tumor angiogenesis and maintenance of the tumor microenvironment and has been implicated in development and metastasis of Hepatocellular carcinoma (HCC). PDGFRA may represent a potential therapeutic target in thymic tumours. PDGFRA gene amplification rather than gene mutation may be the underlying genetic mechanism driving PDGFRA overexpression in a portion of gliomas.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human PDGFRA / CD140a Protein (TMPY-01139) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-PDGFRA Antibody (1K967) | purchase Anti-PDGFRA Antibody (1K967) | Anti-PDGFRA Antibody (1K967) cost | order Anti-PDGFRA Antibody (1K967)
嗨！有任何问题？点我咨询
评论内容