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IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 μg | ¥ 297 | 6-8日内发货 | |
10 μg | ¥ 493 | 6-8日内发货 | |
20 μg | ¥ 786 | 6-8日内发货 | |
50 μg | ¥ 1,560 | 6-8日内发货 | |
100 μg | ¥ 2,630 | In stock | |
200 μg | ¥ 4,160 | 6-8日内发货 | |
500 μg | ¥ 7,670 | 6-8日内发货 | |
1 mg | ¥ 12,200 | 6-8日内发货 |
生物活性 | Immobilized Human IL-17A, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 66.6 ng/ml determined by ELISA (QC Test).Human IL-17R alpha, hFc Tag captured on CM5 Chip via protein A can bind Biotinylated Human IL-17A, His-Avi Tag with an affinity constant of 2.18 nM as determined in SPR assay (Biacore T200). |
产品描述 | IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q96F46-1 |
别名 | interleukin 17 receptor A,IL-17RA,IL17R,hIL-17R,CDw217,CD217,CANDF5 |
蛋白构建 | Leu33-Trp320 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 60.2 kDa (Predicted); 75-90 kDa (Due to glycosylation) |
内毒素 | Less than 1EU per ug by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22. |