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Anti-CD46 Antibody-PE (8C827)
还可以产品编号 TMAY-02294P
Anti-CD46 Antibody-PE (8C827) 是一种 PE-conjugated Mouse 抗体，靶向 CD46。Anti-CD46 Antibody-PE (8C827) 可用于 FCM。
Anti-CD46 Antibody-PE (8C827)
Anti-CD46 Antibody-PE (8C827)
还可以产品编号 TMAY-02294P
Anti-CD46 Antibody-PE (8C827) 是一种 PE-conjugated Mouse 抗体，靶向 CD46。Anti-CD46 Antibody-PE (8C827) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD46 Antibody-PE (8C827) is a PE-conjugated Mouse antibody targeting CD46. Anti-CD46 Antibody-PE (8C827) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8C827 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human CD46 expression on human whole blood lymphocytes. Human whole blood lymphocytes were stained with PE-conjugated anti-Human CD46. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 2 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met1-Asp328) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD46 protein (TMPY-02023) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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