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ATG3 Protein, Human, Recombinant

ATG3 Protein, Human, Recombinant

产品编号 TMPJ-01354
别名: ATG3, Ubiquitin-like-conjugating enzyme ATG3, APG3, Protein PC3-96, Autophagy-related protein 3, APG3-like, APG3L, hApg3

Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

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ATG3 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 620 5日内发货
500 μg ¥ 2,760 5日内发货
1 mg ¥ 3,950 5日内发货
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产品目录号及名称: ATG3 Protein, Human, Recombinant (TMPJ-01354)
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产品描述 Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
种属 Human
表达系统 E. coli
标签 C-6xHis, N-T7
蛋白编号 Q9NT62
别名 ATG3, Ubiquitin-like-conjugating enzyme ATG3, APG3, Protein PC3-96, Autophagy-related protein 3, APG3-like, APG3L, hApg3
氨基酸序列 Met1-Met314
蛋白构建 Met1-Met314
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 38 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

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Keywords

ATG3 Protein, Human, Recombinant ATG3 ATG 3 Ubiquitin-like-conjugating enzyme ATG3 APG3 Protein PC3-96 Autophagy-related protein 3 APG-3 APG 3 APG3-like APG3L ATG-3 hApg3 recombinant recombinant-proteins proteins protein

 

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