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ATG3 Protein, Human, Recombinant

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货号 TMPJ-01354

别名 Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3

Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

ATG3 Protein, Human, Recombinant
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ATG3 Protein, Human, Recombinant

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货号 TMPJ-01354 别名 Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3

Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

规格价格库存数量
5 μg
¥ 148
现货
10 μg
¥ 220
现货
20 μg
¥ 336
现货
50 μg
¥ 620
现货
100 μg
¥ 959
现货
200 μg
¥ 1,480
5日内发货
500 μg
¥ 2,760
5日内发货
1 mg
¥ 3,950
5日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
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产品介绍


生物活性
产品描述
Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.
种属
Human
表达系统
E. coli
标签C-6xHis, N-T7
蛋白编号Q9NT62
氨基酸序列Met1-Met314
蛋白构建Met1-Met314
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.
别名Ubiquitin-like-conjugating enzyme ATG3, Protein PC3-96, hApg3, Autophagy-related protein 3, ATG3, APG3-like, APG3L, APG3
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量38 KDa (reducing condition)
颜色Transparent
物理性状Solution
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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