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Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)

Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)

产品编号 TMPH-00279

Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.8 kDa and the accession number is P15696.

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Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 2,570 20日内发货
100 μg ¥ 4,890 20日内发货
500 μg ¥ 11,300 20日内发货
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产品目录号及名称: Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His) (TMPH-00279)
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产品描述 Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.8 kDa and the accession number is P15696.
种属 Bovine
表达系统 P. pastoris (Yeast)
标签 N-6xHis
蛋白编号 P15696
氨基酸序列 CYLSEDHMLGARENLRLLARMNRLSPHPCLQDRKDFGLPQEMVEGNQLQKDQAISVLHEMLQQCFNLFYTEHSSAAWNTTLLEQLCTGLQQQLEDLDACLGPVMGEKDSDMGRMGPILTVKKYFQGIHVYLKEKEYSDCAWEIIRVEMMRALSSSTTLQKRLRKMGGDLNSL
蛋白构建 24-195 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 21.8 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

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Keywords

recombinant recombinant-proteins proteins protein

 

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