Claudin-6 Protein-VLP, Mouse, Recombinant (His & Flag)

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产品编号 TMPY-07230

Claudin-6 Protein-VLP, Mouse, Recombinant (His & Flag) is expressed in HEK293 Cells. The accession number is Q9Z262.

Claudin-6 Protein-VLP, Mouse, Recombinant (His & Flag)

一键复制产品信息

SPR兼容缓冲液

产品编号 TMPY-07230

Claudin-6 Protein-VLP, Mouse, Recombinant (His & Flag) is expressed in HEK293 Cells. The accession number is Q9Z262.

规格	价格	库存
5 μg	¥ 1,700	6-8日内发货
10 μg	¥ 2,930	6-8日内发货
20 μg	¥ 4,920	5日内发货
50 μg	¥ 7,290	5日内发货
100 μg	¥ 11,300	5日内发货
200 μg	¥ 17,300	5日内发货
500 μg	¥ 42,300	5日内发货

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产品信息

生物活性	Immobilized Recombinant Mouse Claudin-6 Protein (VLP, Full-Length, His-Flag Tag) at 5 μg/mL (100 μL/well) can bind Anti-Claudin-6 Monoclonal Antibody, Human IgG1, the EC50 is 1-5 ng/mL.
产品描述	Claudin-6 Protein-VLP, Mouse, Recombinant (His & Flag) is expressed in HEK293 Cells. The accession number is Q9Z262.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His-Flag
蛋白编号	Q9Z262
别名	Cldn6
蛋白构建	A DNA sequence encoding the Mouse CLDN6 (Full Length) (Q9Z262) (Met1-Val219) was expressed, with a polyhistidine tag followed by a Flag tag at the C-terminus.
分子量	25.76 kDa (predicted)
内毒素	< 1.0 EU per μg protein as determined by the LAL method.
缓冲液	Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
存储	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	It is supplied and shipped as liquid with dry ice.
研究背景	Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.