uPAR/PLAUR 重组蛋白, Human (His & Avi)

uPAR/PLAUR Protein, Human, Recombinant (His & Avi)

产品编号 TMPK-00226

The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 34.36 kDa and the accession number is Q03405-1.

规格	价格	库存
100 μg	¥ 1,320	5日内发货
500 μg	¥ 5,330	5日内发货
1 mg	¥ 8,900	5日内发货

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常见问题解答

问产品是否需要避光？

答一般来说，如果有需要避光储存的分子，我们会选择棕色玻璃瓶发货的。

问超声久了会不会对化合物的结构有影响？

答建议以较低频率对化合物进行超声，不会对化合物的结构造成影响。

问溶解度中写的“< 1 mg/mL refers to the slightly soluble or insoluble ”是什么意思？

答这句话指的是，如果溶解度 < 1 mg/mL，那我们就认为它是微溶或不溶的，这是针对写的“DMSO：Insoluble”或“DMSO：slightly soluble”这类化合物的。

问化合物如何用于动物实验？如何确立剂量、给药方式等？

答同一个化合物对不同动物模型、不同疾病模型的用法不一样，建议根据实验目的，查询文献选择用法。常见的给药方式包括腹腔注射、灌胃等。由于首过效应，一般可以灌胃的也可以腹腔注射，可以腹腔注射的不一定适合灌胃。不同种属的给药剂量可以根据官网的表格换算。但仅供参考，实际应用中可能未必合适或者准确，尽量以具体某种动物给药剂量的参考文献为主。我们的化合物都可以进行细胞动物实验，但有些化合物还没有用于动物实验的文献，这种情况下，您可以尝试进行动物实验，但我们无法提供使用方式，也无法保证药效。

问抑制剂产品应如何储存？

答粉末储存在 -20℃，可以存 3 年以上。母液一般储存于 -80℃，可以存 1 年以上，建议多分装几管，避免反复冻融。常用的存于 4℃，可放一周以上。

产品信息

生物活性	Immobilized Human uPAR, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Human PLAU, His Tag with the EC50 of 9.6ng/ml determined by ELISA.
产品描述	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR. uPAR/PLAUR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 34.36 kDa and the accession number is Q03405-1.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	Q03405-1
别名	U-PAR,uPAR,PLAUR,MO3,CD87
蛋白构建	Leu23-Gly305
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	34.36 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.

uPAR/PLAUR Protein, Human, Recombinant (His & Avi)

uPAR/PLAUR Protein, Human, Recombinant (His & Avi)

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