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B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

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B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

产品编号 TMPK-00314

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.5 kDa and the accession number is Q5ZPR3-1.

B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

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产品编号 TMPK-00314

规格	价格	库存
5 μg	¥ 313	In stock
10 μg	¥ 498	In stock
20 μg	¥ 793	5日内发货
50 μg	¥ 1,580	5日内发货
100 μg	¥ 2,660	In stock
200 μg	¥ 4,790	5日内发货
500 μg	¥ 10,600	5日内发货

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产品信息

生物活性	Immobilized Human B7-H3 (4Ig) , His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA.
产品描述	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.5 kDa and the accession number is Q5ZPR3-1.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	Q5ZPR3-1
别名	UNQ309,PSEC0249,PRO352,CD276,B7-H3,B7 homolog 3, 4Ig-B7-H3
蛋白构建	Gly27-Thr461
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	49.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.