EphB1 Protein, Human, Recombinant (hFc)

Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

规格	价格/CNY		数量
10 μg	￥ 1,170	5日内发货
50 μg	￥ 3,350	5日内发货
500 μg	￥ 17,800	5日内发货
1 mg	￥ 26,700	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

5日内发货

50 μg

￥ 3,350

5日内发货

500 μg

￥ 17,800

5日内发货

1 mg

￥ 26,700

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P54762
别名	EPHT2, EPH Tyrosine Kinase 2, EK6, Tyrosine-Protein Kinase Receptor EPH-2, EPH-Like Kinase 6, EPHB1, Ephrin Type-B Receptor 1, Related Tyrosine Kinase, NET, Neuronally-Expressed EPH, hEK6, ELK
氨基酸序列	Met18-Pro540
蛋白构建	Met18-Pro540
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	85-110 KDa, reducing conditions

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

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EphB1 Protein, Human, Recombinant (hFc)

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