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EphB1 Protein, Human, Recombinant (hFc)

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货号 TMPJ-00403

别名 Tyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6

Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

EphB1 Protein, Human, Recombinant (hFc)

EphB1 Protein, Human, Recombinant (hFc)

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货号 TMPJ-00403 别名 Tyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6

Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

规格价格库存数量
5 μg
¥ 693
6-8日内发货
10 μg
¥ 1,170
6-8日内发货
20 μg
¥ 1,830
2-4周
50 μg
¥ 3,350
2-4周
100 μg
¥ 5,520
2-4周
200 μg
¥ 9,130
2-4周
500 μg
¥ 17,800
2-4周
1 mg
¥ 26,700
2-4周
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产品介绍


生物活性
产品描述
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号P54762
氨基酸序列Met18-Pro540
蛋白构建Met18-Pro540
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Tyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量85-110 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

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