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Anti-IFNAR1 Antibody (1J643)

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产品编号 TMAY-02546
别名 interferon (α, β and Ω) receptor 1, interferon (α, β and ω) receptor 1, interferon (alpha, beta and omega) receptor 1

Anti-IFNAR1 Antibody (1J643) 是一种 Mouse 抗体,靶向 IFNAR1。Anti-IFNAR1 Antibody (1J643) 可用于 ELISA。

Anti-IFNAR1 Antibody (1J643)

Anti-IFNAR1 Antibody (1J643)

Rating icon 还可以
产品编号 TMAY-02546 别名 interferon (α, β and Ω) receptor 1, interferon (α, β and ω) receptor 1, interferon (alpha, beta and omega) receptor 1

Anti-IFNAR1 Antibody (1J643) 是一种 Mouse 抗体,靶向 IFNAR1。Anti-IFNAR1 Antibody (1J643) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

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产品描述
Anti-IFNAR1 Antibody (1J643) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (1J643) can be used in ELISA.
别名interferon (α, β and Ω) receptor 1, interferon (α, β and ω) receptor 1, interferon (alpha, beta and omega) receptor 1
Ig Type
Monoclonal Mouse IgG1
克隆号
1J643
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This product is a recombinant monoclonal antibody expressed from HEK293 cells.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant-negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IFNAR1 / IFNAR protein (TMPY-02647)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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