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PRKRA Protein, Bovine, Recombinant (His & Myc)

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货号 TMPH-00280

别名 Protein kinase, interferon-inducible double-stranded RNA-dependent activator, Protein activator of the interferon-induced protein kinase, PRKRA, Interferon-inducible double-stranded RNA-dependent protein kinase activator A

PRKRA Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q2HJ92.

PRKRA Protein, Bovine, Recombinant (His & Myc)
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PRKRA Protein, Bovine, Recombinant (His & Myc)

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货号 TMPH-00280 别名 Protein kinase, interferon-inducible double-stranded RNA-dependent activator, Protein activator of the interferon-induced protein kinase, PRKRA, Interferon-inducible double-stranded RNA-dependent protein kinase activator A

PRKRA Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q2HJ92.

规格价格库存数量
5 μg
¥ 825
20日内发货
10 μg
¥ 1,360
20日内发货
20 μg
¥ 2,290
20日内发货
50 μg
¥ 3,460
20日内发货
100 μg
¥ 4,750
20日内发货
200 μg
¥ 6,830
20日内发货
500 μg
¥ 10,800
20日内发货
1 mg
¥ 16,000
20日内发货
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产品介绍


生物活性
产品描述
PRKRA Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q2HJ92.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at 'Lys-386' at 'Ser-392' respectively and enhances its activity in a EIF2AK2/PKR-dependent manner.
种属
Bovine
表达系统
E. coli
标签N-10xHis, C-Myc
蛋白编号Q2HJ92
氨基酸序列MSQSRHRAAAPPMEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNMVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCSSAQSDAAHNALQYLKIIAERK
蛋白构建1-313 aa
蛋白纯度
> 85% as determined by SDS-PAGE.
缓冲液Tris-based buffer, 50% glycerol
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名Protein kinase, interferon-inducible double-stranded RNA-dependent activator, Protein activator of the interferon-induced protein kinase, PRKRA, Interferon-inducible double-stranded RNA-dependent protein kinase activator A
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量39.4 kDa (predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

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