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ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate 是一种合成化合物,属于姜黄素家族。它通过抑制NF-κB 信号通路参与免疫反应和炎症的调节,通过激活Nrf2信号通路参与抗氧化反应的调节,通过抑制Akt 信号通路参与细胞存活和增殖的调节。
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ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate 是一种合成化合物,属于姜黄素家族。它通过抑制NF-κB 信号通路参与免疫反应和炎症的调节,通过激活Nrf2信号通路参与抗氧化反应的调节,通过抑制Akt 信号通路参与细胞存活和增殖的调节。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 791 | In stock | |
5 mg | ¥ 1,850 | In stock | |
10 mg | ¥ 2,770 | In stock | |
25 mg | ¥ 4,160 | In stock | |
50 mg | ¥ 5,580 | In stock | |
100 mg | ¥ 7,420 | In stock | |
200 mg | ¥ 10,000 | In stock | |
1 mL x 10 mM (in DMSO) | ¥ 1,890 | In stock |
产品描述 | ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through inhibition of the NF-κB signaling pathway, in the regulation of antioxidant response through activation of the Nrf2 signaling pathway, and in the regulation of cell survival and proliferation through inhibition of the Akt signaling pathway. |
分子量 | 368.23 |
分子式 | C14H10F6N2O3 |
CAS No. | 1878204-21-7 |
Smiles | O=C1N(NC=C1C(OCC)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2 |
密度 | 1.479 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (135.78 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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