购物车

您的购物车当前为空

L-Proline

Name: L-Proline
Brand: TargetMol
SKU: T2O2683
Price: 132 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 98.05%

货号 T2O2683Cas号 147-85-3

别名 脯氨酸, proline, L-脯氨酸, L-(-)-Proline

L-Proline (proline) 是人体非必需氨基酸。它是胶原蛋白的重要组成部分，对关节和肌腱的正常运作很重要。它还有助于维持和加强心脏肌肉。

L-Proline

一键复制产品信息

很棒

纯度: 98.05%

货号 T2O2683 别名 脯氨酸, proline, L-脯氨酸, L-(-)-ProlineCas号 147-85-3

L-Proline (proline) 是人体非必需氨基酸。它是胶原蛋白的重要组成部分，对关节和肌腱的正常运作很重要。它还有助于维持和加强心脏肌肉。

规格	价格	库存
100 mg	¥ 132	现货
500 mg	¥ 330	现货
5 g	¥ 413	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 98.05%

联系我们获取更多批次信息

资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

生物活性

产品描述	L-Proline (proline) is a nonessential amino acid in humans. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles.
别名	脯氨酸, proline, L-脯氨酸, L-(-)-Proline

化学信息

分子量	115.13
分子式	C₅H₉NO₂
CAS No.	147-85-3
Smiles	OC(=O)[C@@H]1CCCN1
密度	1.35 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: Insoluble

H2O: 10 mM, Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	8.6858 mL	43.4292 mL	86.8583 mL	434.2917 mL
5 mM	1.7372 mL	8.6858 mL	17.3717 mL	86.8583 mL
10 mM	0.8686 mL	4.3429 mL	8.6858 mL	43.4292 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20g，给药体积100 μL， TargetMol | Animal experiments

一共给药动物10只，您使用的配方为5% TargetMol | reagent

DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline /PBS/ddH₂O，那么您的工作液浓度为2mg/mL。

母液配置方法: 2 mg 药物溶于 50 μLDMSO TargetMol | reagent

（母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法: 取 50μLDMSO TargetMol | reagent

母液，添加 300 μLPEG300 TargetMol | reagent

混匀澄清，再加 50μLTween80, 混匀澄清，再加 600μLSaline /PBS/ddH₂O TargetMol | reagent

混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO ， PEG300 / PEG400 ， Tween 80 ， SBE-β-CD ，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

TargetMol AI Summary

L-Proline has a bitter taste, with a Log 1/T value of 1.59 and a partition coefficient (logP) of 2.5. It exhibits bioactivity across various biological targets and assays. For instance, it inhibits the binding of [3H]strychnine to NMDA glutamate receptor 1 with an IC50 of 414000.0 nM and demonstrates potency in modulating Lamin A splicing with a potency of 199.5 nM. Additionally, it has inhibitory activity against Anthrax Lethal Toxin internalization with a potency of 398.1 nM and human PAT1-mediated L-[3H]proline uptake with a Ki value of 1600000.0 nM. The compound also enhances systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew in white cabbage, reducing infected leaf areas by 59.3% to 99.2%. In enzyme inhibition studies, L-Proline inhibits ACE with a Ki of 86000.0 nM and exhibits 93% inhibition at 500 μM. It also inhibits L-serine uptake by ASCT2, PKM2 activity by 65.0%, and allosterically inhibits Escherichia coli G5K with an IC50 of 2.5 μM, achieving 100% inhibition. However, it demonstrated limited antiviral activity against SARS-CoV-2 with a hit score of 0.14 and showed an inhibition of 12.0% on human Microsomal Epoxide Hydrolase at 50 μM. Despite its varied bioactivities, L-Proline did not show significant activity (AC50 > 30000.0 nM) against numerous receptors and enzymes such as dopamine receptors, potassium channels, serotonin transporters, and others in multiple assays..

Note: Summary generated by AI, AI may be wrong some times, we do not provide any medical advice and only sell our product to accredited institution, Please cross-check with other sources, data source: chembl